Pitavastatin Calcium

Basic Information

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CAS Number

147526-32-7

Molecular Formula

C50H46CaF2N2O8

Molecular Weight

880.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

219-230°C

Boiling Point

692°C at 760 mmHg

Flash Point

372.3 °C

Specific Rotation

23.4° (c=1.0, in acetonitrile/H2O)

SMILES

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C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2]

InChI

InChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1

InChIKey

RHGYHLPFVJEAOC-FFNUKLMVSA-L

LogP

6.36680

Complexity

626

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Itavastatin calcium
Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate) monocalcium salt
NKS-104
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid hemicalcium salt
6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-
NCGC00356953-01
Alipza
UNII-IYD54XEG3W
Livalo
calcium;(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
Pitavastatin calcium salt
6-Heptenoic acid, 7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)-3,5-dihydroxy-, calcium salt (2:1), (S-(R*,S*-(E)))-
calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate}
calcium (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
Monocalcium bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate)
Redevant
Q-201590
DTXSID4046448
PITAVASTATIN CALCIUM SALT [MI]
Pitavastatin hemicalcium
CHEBI:71258
Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
calcium bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate)
Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate), monocalcium salt
Pitavastatin calcium
NK 104
DTXCID40819916
Tox21_303926
Flovas
MFCD01937979

MDL Number

MFCD01937979

Customs Code

29339900

FAQ

What is Pitavastatin Calcium (CAS: 147526-32-7)?

Pitavastatin Calcium is a statin medication used to lower cholesterol levels. It has the chemical formula C26H32CaN2O7 and is a white to off-white powder. This compound is known for its stability and effectiveness in inhibiting HMG-CoA reductase, a key enzyme in cholesterol synthesis. It is commonly prescribed for the management of hyperlipidemia.

What are the main uses of Pitavastatin Calcium (CAS: 147526-32-7)?

Pitavastatin Calcium is primarily used in the treatment of high cholesterol and other lipid disorders. It helps reduce low-density lipoprotein (LDL) cholesterol, triglycerides, and increase high-density lipoprotein (HDL) cholesterol. This medication is also used in research for studying lipid metabolism and cardiovascular diseases.

Is Pitavastatin Calcium (CAS: 147526-32-7) safe?

Pitavastatin Calcium is generally considered safe when used as directed. However, like all medications, it may cause side effects such as muscle pain or liver function changes. It is important to follow safety guidelines and consult a healthcare professional before use. Proper handling and storage are essential to maintain its efficacy and safety.

How should Pitavastatin Calcium (CAS: 147526-32-7) be stored?

Pitavastatin Calcium should be stored in a cool, dry place away from moisture and light. It is typically kept at a temperature between 15°C to 30°C (59°F to 86°F). Ensure the container is tightly sealed to prevent exposure to air. Proper storage helps maintain its chemical stability and potency over time.