4-Chlorophenylalanine hydrochloride (1:1)

Basic Information

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CAS Number

147065-05-2

Molecular Formula

C9H11Cl2NO2

Molecular Weight

236.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

235°C

Boiling Point

339.5°Cat760mmHg

Density

1.336

Flash Point

159.1°C

Refractive Index

10 ° (C=1, H2O)

SMILES

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C1=CC(=CC=C1CC(C(=O)O)N)Cl.Cl

InChI

InChI=1S/C9H10ClNO2.ClH/c10-7-3-1-6(2-4-7)5-8(11)9(12)13;/h1-4,8H,5,11H2,(H,12,13);1H/t8-;/m1./s1

InChIKey

PFOCEDBJFKVRHU-DDWIOCJRSA-N

LogP

1.7162

Topological Polar Surface Area

63.31999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

179

Synonyms & References

English

SCHEMBL16825893
AKOS015891229
AKOS015845863
(R)-2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride
UNII-BD72V2FZ8G
4-Chloro-D-phenylalanine Hydrochloride
D-Phenylalanine, 4-chloro-, hydrochloride (1:1)
(2R)-2-amino-3-(4-chlorophenyl)propanoic acid;hydrochloride
4-Chloro-D-phenylalanine HCl
(d)-4-Chlorophenylalanine hydrochloride
GS-2602
(2R)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOIC ACID HYDROCHLORIDE
N12343
Fenclonine hydrochloride, (R)-
BD72V2FZ8G
CS-0201595
4-Chloro-D-Phenylalanine.HCl
147065-05-2
HY-W141798
MFCD03095607
4-Chloro-D-phenylalanine
(R)-2-Amino-3-(4-chlorophenyl)propionic Acid Hydrochloride
(R)-4-Chlorophenylalanine Hydrochloride Salt
4-chloro-d-pheny
4-CHLORO-D-PHENYLALAINE HYDROCHLORIDE
4-CHLORO-D-PHENYLALANINE HCL
D-(4-CHLORO-PHENYL)ALANINE HYDROCHLORIDE
H-D-PHE(4-CL)-OH HCL
H-D-PHE(P-CL)-OH HCL
P-CHLORO-D-PHENYLALANINE HCL
H-D-Phe(4-Cl)-OH·HCl

MDL Number

MFCD03095607

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2)?

4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2) is a white crystalline powder. Its molecular weight is approximately 240.57 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is stable in neutral and acidic media but can hydrolyze in alkaline conditions. It is not flammable and is not reactive towards common oxidizing or reducing agents.

How is 4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2) typically synthesized?

4-Chlorophenylalanine hydrochloride can be synthesized by reacting 4-chloroaniline with phenylacetic acid in the presence of a suitable acid catalyst, such as sulfuric acid, followed by recrystallization from water or an aqueous solution to obtain the desired hydrochloride salt. The reaction yields are generally high, and the product can be isolated with good purity.

What industries use 4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2)?

4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of specialty polymers, and in the semiconductor industry for the development of sensors and other electronic components. It also finds applications in research and development for its unique chemical properties.

What precautions should be taken when handling 4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2)?

When handling 4-Chlorophenylalanine hydrochloride (CAS: 147065-05-2), it is essential to wear appropriate personal protective equipment, including gloves, safety goggles, and a laboratory coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and disposed of appropriately according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.