(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine

Basic Information

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CAS Number

146476-37-1

Molecular Formula

C17H22NP

Molecular Weight

271.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Refractive Index

n20/D 1.597

SMILES

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CC(C)C(CP(C1=CC=CC=C1)C2=CC=CC=C2)N

InChI

InChI=1S/C17H22NP/c1-14(2)17(18)13-19(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,14,17H,13,18H2,1-2H3/t17-/m1/s1

InChIKey

ZZLCXURCZWQECA-QGZVFWFLSA-N

LogP

3.1026000000000016

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

224

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine
(S)-1-(Diphenylphosphino)-3-methyl-2-butylamine
(1S)-1-(diphenylphosphino)
(2S)-1-(diphenylphosphino)-3-methylbutan-2-amine
(2S)-2-amino-1-(diphenylphosphino)-3-methylbutane
(2S)-2-amino-1-(diphenylphosphinyl)-3-methylbutane
(S)-1-(DIPHENYLPHOSPHINO)-2-AMINO-3-METHYLBUTANE
(S)-1-(diphenylphosphino)-3-methyl-2-butanamine
(S)-1-(diphenylphosphinomethyl)-2-methyl-propylamine
(S)-2-AMINO-1-DIPHENYLPHOSPHINO-3-METHYLBUTANE
KB-210699
(S)-(+)-ValPHOS
(S)-(2-Amino-3-methylbutyl)diphenylphosphine
(2S)-1-diphenylphosphanyl-3-methylbutan-2-amine
(2S)-1-(diphenylphosphino)-3-Methyl-2-ButanaMine
(S)-1-(Diphenylphosphino)-3-Methyl-2-butylaMine
(S)-1-(Diphenylphosphino)-2-aMino-3-Methylbutane
(S)-2-AMino-1-diphenylphosphino-3-Methylbutane, 97+%
(S)-1-(Diphenylphosphino)-2-amino-3-methylbutane, min. 97%
(S)-1-(Diphenylphosphino)-2-amino-3-methylbutane, min. 97per cent
CS-W010096
SCHEMBL17513104
(2S)-1-(Diphenylphosphanyl)-3-methylbutan-2-amine
(S)-1-(DIPHENYLPHOSPHINO)-3-METHYL-2-BUTYLAMINE
DTXSID90569035
D94511
MFCD17013993
2-Butanamine, 1-(diphenylphosphino)-3-methyl-, (2S)-
C17H22NP
[(2S)-2-AMINO-3-METHYLBUTYL]DIPHENYLPHOSPHANE
WFA47637

MDL Number

MFCD17013993

FAQ

What is (S)-1-(Diphenylphosphino)-3-methylbutan-2-amine (CAS: 146476-37-1)?

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is a chiral organophosphine ligand with the CAS number 146476-37-1. It is a colorless to white crystalline solid with a faintly aromatic odor. This compound is known for its high thermal stability and good solubility in organic solvents.

What are the main uses of (S)-1-(Diphenylphosphino)-3-methylbutan-2-amine (CAS: 146476-37-1)?

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is widely used as a chiral ligand in homogeneous catalysis, particularly in the asymmetric hydrogenation of alkenes and ketones. It is also utilized in pharmaceutical synthesis and as a reagent in organic synthesis due to its high chiral induction ability.

Is (S)-1-(Diphenylphosphino)-3-methylbutan-2-amine (CAS: 146476-37-1) safe?

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is generally considered safe when handled with proper precautions. However, it should be stored in a cool, dry place away from moisture and direct sunlight. Protective gloves and eye protection should be worn during handling to avoid skin contact and inhalation. In case of accidental ingestion, seek medical attention immediately.

How should (S)-1-(Diphenylphosphino)-3-methylbutan-2-amine (CAS: 146476-37-1) be stored?

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine should be stored in a cool, dry place with a temperature range between 15-25°C and a relative humidity below 60%. It should be kept away from direct sunlight, moisture, and oxidizing agents. Storage in a sealed container is recommended to prevent degradation and loss of activity. Use a borosilicate glass container lined with a Teflon cap for optimal storage conditions.