(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine(CAS: 146476-37-1)

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is a chiral organophosphine ligand with the CAS number 146476-37-1. It is a colorless to white crystalline solid with a faintly aromatic odor. This compound is known for its high thermal stability and good solubility in organic solvents.

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is widely used as a chiral ligand in homogeneous catalysis, particularly in the asymmetric hydrogenation of alkenes and ketones. It is also utilized in pharmaceutical synthesis and as a reagent in organic synthesis due to its high chiral induction ability.

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine is generally considered safe when handled with proper precautions. However, it should be stored in a cool, dry place away from moisture and direct sunlight. Protective gloves and eye protection should be worn during handling to avoid skin contact and inhalation. In case of accidental ingestion, seek medical attention immediately.

(S)-1-(Diphenylphosphino)-3-methylbutan-2-amine should be stored in a cool, dry place with a temperature range between 15-25°C and a relative humidity below 60%. It should be kept away from direct sunlight, moisture, and oxidizing agents. Storage in a sealed container is recommended to prevent degradation and loss of activity. Use a borosilicate glass container lined with a Teflon cap for optimal storage conditions.