Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate | CAS No. 146118-22-1
Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate
Basic Information
CAS Number
146118-22-1
Molecular Formula
C20H18N2O6
Molecular Weight
382.37 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Benzyl {(1S)-2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxo-1-phenylethyl}carbamate
- (S)-2,5-Dioxopyrrolidin-1-yl2-(((benzyloxy)carbonyl)amino)-2-phenylacetate
- 146118-22-1
- (2,5-dioxopyrrolidin-1-yl) (2S)-2-phenyl-2-(phenylmethoxycarbonylamino)acetate
- Z-PHG-OSU
- (S)-2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)-carbonyl)amino)-2-phenylacetate
- S-146118-22-1
- N-alpha-BenZyloxycarbonyl-L-phenylglycine succinimidyl ester (CbZ-L-Phg-OSu)
- Z-L-Phg-OSu
- AKOS016001306
- Carbamic acid, [(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl]-, phenylmethyl ester
- MZJSWDYNUOPUKB-SFHVURJKSA-N
- (S)-2,5-dioxopyrrolidin-1-yl 2-(benzyloxycarbonylamino)-2-phenylacetate
- (S)-2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-2-phenylacetate
- DTXSID80679834
- 2,5-DIOXOPYRROLIDIN-1-YL (2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-2-PHENYLACETATE
- MFCD00153339
- Carbamic acid,[(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl]-, phenylmethylester (9CI)
- Carbamic acid,[(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl]-, phenylmethylester...
- Z-PhGly-OSu
- CBZ-PHG-Osu
- Z-PHENYLGLYCINE-OSU
- Z-L-PHENYLGLYCINE N-HYDROXYSUCCINIMIDE ESTER
- Cbz-L-Phenylglycine N-hydroxysuccinimide ester
- N-alpha-Benzyloxycarbonyl-L-phenylglycine succinimidyl ester
- BENZYLOXYCARBONYL-L-PHENYLGLYCINE N-HYDROXYSUCCINIMIDE ESTER
- N-ALPHA-CARBOBENZOXY-L-PHENYLGLYCINE N-HYDROXYSUCCINIMIDE ESTER
MDL Number
MFCD00153339
Customs Code
2925190090
FAQ
What are the physical and chemical properties of Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate (CAS: 146118-22-1)?
Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate is a crystalline compound with a molecular weight of approximately 429.45 g/mol. It is slightly soluble in water but more soluble in organic solvents such as methanol and ethanol. The compound is known for its reactivity towards nucleophiles and its ability to undergo hydrolysis under basic conditions.
How is Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate (CAS: 146118-22-1) typically synthesized?
Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate is typically synthesized through a multi-step process involving the condensation of a benzylamine with a pyrrolidone derivative. The reaction involves the use of a base catalyst such as potassium carbonate and is carried out in an organic solvent like dimethylformamide (DMF). The overall yield and selectivity of the reaction can be enhanced by optimizing reaction conditions such as temperature and time.
What industries use Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate (CAS: 146118-22-1)?
Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry for the modification of polymer properties and in the semiconductor industry for the fabrication of sensitive components. Additionally, it finds application in the development of chemical sensors due to its unique reactivity.
What precautions should be taken when handling Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate (CAS: 146118-22-1)?
When handling Benzyl {(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-phenylethyl}carbamate, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to minimize exposure to vapors. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be thoroughly ventilated. Safety data sheets (SDS) should be consulted for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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