2-Ethoxypyridine

Basic Information

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CAS Number

14529-53-4

Molecular Formula

C7H9NO

Molecular Weight

123.15 g/mol

EINECS

238-553-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

122 °C

Boiling Point

155-156°C

Density

1,009 g/cm3

Flash Point

155-156°C

Refractive Index

1.4960

SMILES

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CCOC1=CC=CC=N1

InChI

InChI=1S/C7H9NO/c1-2-9-7-5-3-4-6-8-7/h3-6H,2H2,1H3

InChIKey

LISKAOIANGDBTB-UHFFFAOYSA-N

LogP

1.4803

pKa

4.09±0.12(Predicted)

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

75.3

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

MFCD00023464
14529-53-4
Pyridine, 2-ethoxy-
InChI=1/C7H9NO/c1-2-9-7-5-3-4-6-8-7/h3-6H,2H2,1H
AC-907/25014179
ethyl 2-pyridinyl ether
CARAZOLOL HCL
AI3-60422
AKOS005258151
EINECS 238-553-7
4G3BKY7JKQ
2-Ethoxy pyridine
Q-100167
SCHEMBL152133
AM20061677
CS-W017767
2-Ethoxy-pyridine
AS-31090
CHEMBL3274301
E0870
DTXSID70162967
UNII-4G3BKY7JKQ
FT-0612224
NS00024725
SB52293
AC-23102
A3158
2-Ethoxypyridine
SPECS AC-907/25014179
2-ETHOXYPYRIDINE
2-ETHOXY PYRIDINE FEMA NO.--------

MDL Number

MFCD00023464

EC Number

238-553-7

Customs Code

29333990

FAQ

What are the physical and chemical properties of 2-Ethoxypyridine (CAS: 14529-53-4)?

2-Ethoxypyridine (CAS: 14529-53-4) is a yellowish-brown liquid with a molecular weight of approximately 121.18 g/mol. It has a boiling point of 135-136°C and a melting point of -21°C. This compound is slightly soluble in water but highly soluble in organic solvents. It is mildly reactive, particularly with strong oxidizing agents and can undergo substitution reactions.

How is 2-Ethoxypyridine (CAS: 14529-53-4) typically synthesized?

2-Ethoxypyridine is typically synthesized by the reaction of pyridine with ethanol in the presence of sulfuric acid as a catalyst. The reaction is exothermic and proceeds to give an isolated yield of 75-80%. The product is usually obtained in a crystalline form after recrystallization from suitable solvents.

What industries use 2-Ethoxypyridine (CAS: 14529-53-4)?

2-Ethoxypyridine (CAS: 14529-53-4) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also used in the production of organic semiconductors and as a precursor in the polymer industry. Additionally, it finds applications in sensor technologies due to its ability to interact with specific analytes.

What precautions should be taken when handling 2-Ethoxypyridine (CAS: 14529-53-4)?

When handling 2-Ethoxypyridine (CAS: 14529-53-4), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to avoid inhalation of vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.