2-Ethoxypyridine(CAS: 14529-53-4)

2-Ethoxypyridine (CAS: 14529-53-4) is a yellowish-brown liquid with a molecular weight of approximately 121.18 g/mol. It has a boiling point of 135-136°C and a melting point of -21°C. This compound is slightly soluble in water but highly soluble in organic solvents. It is mildly reactive, particularly with strong oxidizing agents and can undergo substitution reactions.

2-Ethoxypyridine is typically synthesized by the reaction of pyridine with ethanol in the presence of sulfuric acid as a catalyst. The reaction is exothermic and proceeds to give an isolated yield of 75-80%. The product is usually obtained in a crystalline form after recrystallization from suitable solvents.

2-Ethoxypyridine (CAS: 14529-53-4) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also used in the production of organic semiconductors and as a precursor in the polymer industry. Additionally, it finds applications in sensor technologies due to its ability to interact with specific analytes.

When handling 2-Ethoxypyridine (CAS: 14529-53-4), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to avoid inhalation of vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.