4-(4-Chlorophenyl)cyclohexanone

Basic Information

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CAS Number

14472-80-1

Molecular Formula

C12H13ClO

Molecular Weight

208.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CC(=O)CCC1C2=CC=C(C=C2)Cl

InChI

InChI=1S/C12H13ClO/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-2,5-6,10H,3-4,7-8H2

InChIKey

JNBOVWFOTNYTES-UHFFFAOYSA-N

LogP

3.5667000000000018

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

196

Synonyms & References

English

AMY15784
4-(p-Chlorophenyl)cyclohexanone
SB66795
A808274
CS-W019468
4-(4-chlorophenyl)cyclohexan-1-one
4-(4-chloro-phenyl)-cyclohexanone
C72741
AC-26582
14472-80-1
MFCD11850091
DTXSID20562251
SCHEMBL3536658
4-(4-Chlorophenyl)cyclohexanone
AKOS015890365
4-(4'-Chlorophenyl)cyclohexanone
Cyclohexanone, 4-(4-chlorophenyl)-
4-(4-chlorophenyl)-1-cyclohexanone
J-513487
DS-13281
CYC011
RL01808
AS04540
AX8122739
ST24042944
472C801

MDL Number

MFCD11850091

Customs Code

2914700090

FAQ

What are the physical and chemical properties of 4-(4-Chlorophenyl)cyclohexanone (CAS: 14472-80-1)?

4-(4-Chlorophenyl)cyclohexanone has a crystalline form with a molecular weight of 228.59 g/mol. It is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. The compound is known for its moderate reactivity, particularly towards nucleophiles, and is stable under normal laboratory conditions.

How is 4-(4-Chlorophenyl)cyclohexanone (CAS: 14472-80-1) typically synthesized?

4-(4-Chlorophenyl)cyclohexanone is commonly synthesized through the condensation of chlorophenol with cyclohexanone using a base like sodium hydroxide. The reaction is carried out in an aqueous phase, and the product is isolated by extraction with organic solvents. Catalysts such as sodium carbonate can improve yield and selectivity.

What industries use 4-(4-Chlorophenyl)cyclohexanone (CAS: 14472-80-1)?

4-(4-Chlorophenyl)cyclohexanone is used in the pharmaceutical industry for the synthesis of certain organic compounds and intermediates. It also finds applications in the polymer industry for the production of certain resins and in the sensor industry for gas detection applications.

What precautions should be taken when handling 4-(4-Chlorophenyl)cyclohexanone (CAS: 14472-80-1)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 4-(4-Chlorophenyl)cyclohexanone. It should be stored in a well-ventilated area and fume hoods should be used during handling. In case of spill, it should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Refer to the safety data sheet (SDS) for detailed information.