Compound Q&A

How is 4-(4-Chlorophenyl)cyclohexanone (CAS: 14472-80-1) typically synthesized?

Answer

4-(4-Chlorophenyl)cyclohexanone
4-(4-Chlorophenyl)cyclohexanone is commonly synthesized through the condensation of chlorophenol with cyclohexanone using a base like sodium hydroxide. The reaction is carried out in an aqueous phase, and the product is isolated by extraction with organic solvents. Catalysts such as sodium carbonate can improve yield and selectivity.

About

CAS No 14472-80-1
English Name 4-(4-Chlorophenyl)cyclohexanone
Molecular Formula C12H13ClO
Molecular Weight 208.68799999999996 g/mol
SMILES C1CC(=O)CCC1C2=CC=C(C=C2)Cl
InChIKey JNBOVWFOTNYTES-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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