4-(4-Chlorophenyl)cyclohexanone(CAS: 14472-80-1)

4-(4-Chlorophenyl)cyclohexanone has a crystalline form with a molecular weight of 228.59 g/mol. It is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. The compound is known for its moderate reactivity, particularly towards nucleophiles, and is stable under normal laboratory conditions.

4-(4-Chlorophenyl)cyclohexanone is commonly synthesized through the condensation of chlorophenol with cyclohexanone using a base like sodium hydroxide. The reaction is carried out in an aqueous phase, and the product is isolated by extraction with organic solvents. Catalysts such as sodium carbonate can improve yield and selectivity.

4-(4-Chlorophenyl)cyclohexanone is used in the pharmaceutical industry for the synthesis of certain organic compounds and intermediates. It also finds applications in the polymer industry for the production of certain resins and in the sensor industry for gas detection applications.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 4-(4-Chlorophenyl)cyclohexanone. It should be stored in a well-ventilated area and fume hoods should be used during handling. In case of spill, it should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Refer to the safety data sheet (SDS) for detailed information.