Piperazine citrate

Basic Information

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CAS Number

144-29-6

Molecular Formula

C24H46N6O14

Molecular Weight

278.26 g/mol

EINECS

205-622-8

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

183-187℃

Boiling Point

208℃[at 101 325 Pa]

Density

0.741[at 20℃]

Water Solubility

54g/L at 24℃

Vapor Pressure

56.928Pa

SMILES

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OC(C(O)=O)(CC(O)=O)CC(O)=O.N1CCNCC1

InChI

InChI=1S/C6H8O7.C4H10N2/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-2-6-4-3-5-1/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);5-6H,1-4H2

InChIKey

SWDXALWLRYIJHK-UHFFFAOYSA-N

LogP

-2.0692999999999975

Topological Polar Surface Area

156.19000000000003 Å²

Hydrogen Bond Donor/Acceptor

6 / 9

Complexity

254

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

ANTEPAR
CITRIC ACID SESQUIPIPERAZINE SALT
PIPERAZINE CITRATE
PIPERAZINE CITRATE SALT
PARAZINE
TRIPIPERAZINE DICITRATE
PiperazineCitrateBp
Tripiperazindicitrat
Piperazine citrate
tripiperazine dicitrate
Piperazine Citrate Hydrate
Piperazine (citrate)
Piperazine Citrate n-Hydrate
Citraazine
Coliurinal
Patazine
Pinozan
Piperasol
Piperazin,Cirate
Piperazincitrat
piperazine,cirate
Anthecole
Antoban
Arpezine
Ascarex Syrup
Bryrel
Exelmin
Exopin
Helmezine
Multifuge
Multifuge Citrate

MDL Number

MFCD00038961

EC Number

205-622-8

Customs Code

29335990

FAQ

What are the physical and chemical properties of Piperazine citrate (CAS: 144-29-6)?

Piperazine citrate is a white crystalline solid with a molecular weight of approximately 252.27 g/mol. It is moderately soluble in water and has limited solubility in organic solvents. Chemically, it shows basic properties due to the presence of piperazine and citric acid. It is stable under normal conditions but can react with strong acids to form piperazine and citric acid.

How is Piperazine citrate (CAS: 144-29-6) typically synthesized?

Piperazine citrate can be synthesized by reacting piperazine with citric acid. The reaction involves the formation of a salt between piperazine and citric acid. Commonly, this process is carried out in aqueous solution at room temperature. The yield is typically high, with a selectivity towards the desired product, and the process is straightforward without the need for complex catalysts.

What industries use Piperazine citrate (CAS: 144-29-6)?

Piperazine citrate is utilized in various industries. In the pharmaceutical industry, it serves as a buffering agent in formulations. In polymers, it can act as a stabilizer and improve the properties of polymer products. Additionally, it has applications in sensors as a pH indicator and in semiconductors as a dopant.

What precautions should be taken when handling Piperazine citrate (CAS: 144-29-6)?

When handling Piperazine citrate, it is important to use personal protective equipment (PPE), such as gloves and goggles, to protect against skin contact and eye exposure. It should be stored in a cool, dry place, away from strong acids which can react with it. In case of spill, it should be cleaned up immediately using appropriate procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.