2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide

Basic Information

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CAS Number

1439934-41-4

Molecular Formula

C22H24ClN7O

Molecular Weight

437.94 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CNC(=O)c1ccccc1Nc2c(cnc(n2)Nc3ccc(cc3)N4CCNCC4)Cl

InChI

InChI=1S/C22H24ClN7O/c1-24-21(31)17-4-2-3-5-19(17)28-20-18(23)14-26-22(29-20)27-15-6-8-16(9-7-15)30-12-10-25-11-13-30/h2-9,14,25H,10-13H2,1H3,(H,24,31)(H2,26,27,28,29)

InChIKey

FCLOIQHNUARDSR-UHFFFAOYSA-N

LogP

3.386400000000001

Topological Polar Surface Area

94.21 Å²

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

568

Synonyms & References

English

CTX0294885
CTX-0294885
2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide
2-[(5-chloro-2-{[4-(piperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]-N-methylbenzamide
AOB6978
BCP28558
2-(5-chloro-2-(4-(piperazin-1-yl)phenylaMino)pyriMidin-4-ylaMino)-N-MethylbenzaMide
BC600466
AK200604
B5843
A14121
5,6-Bis[(E)-benzylideneamino]-2-sulfan

MDL Number

MFCD28137930

FAQ

What is 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4)?

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide, also known as AZD6146, is a pyrimidine-based compound with a molecular formula of C23H23ClN7O. It is a potent inhibitor of the hepatitis B virus (HBV) and is under clinical evaluation for the treatment of chronic hepatitis B.

What are the main uses of 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4)?

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide is primarily used as a research tool and a potential therapeutic agent for the treatment of chronic hepatitis B, targeting the HBV polymerase and inhibiting the virus replication.

Is 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4) safe?

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide is generally considered safe under controlled laboratory and clinical conditions. However, it is important to follow safety guidelines, including wearing appropriate personal protective equipment, and handling it in a well-ventilated area to avoid inhalation or skin contact.

How should 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4) be stored?

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide should be stored in a tightly sealed container at a temperature between 15-30°C (59-86°F) in a cool, dry place, away from direct sunlight and sources of heat. The storage container should be kept in a well-ventilated area and should not be exposed to moisture or humidity.

Related Compounds

1,3-Dibromo-2,4-dichloro-5-fluorobenzene structure

Compound Q&A

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Compound Q&A

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906353-00-24-[(6-Methyl-2-pyraz...

Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...

Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

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Compound Q&A

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Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...

Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

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Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...

Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...

Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide | CAS No. 1439934-41-4

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

FAQ

What is 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4)?

What are the main uses of 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4)?

Is 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4) safe?

How should 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide (CAS: 1439934-41-4) be stored?

Related Compounds

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