2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide(CAS: 1439934-41-4)

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide, also known as AZD6146, is a pyrimidine-based compound with a molecular formula of C23H23ClN7O. It is a potent inhibitor of the hepatitis B virus (HBV) and is under clinical evaluation for the treatment of chronic hepatitis B.

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide is primarily used as a research tool and a potential therapeutic agent for the treatment of chronic hepatitis B, targeting the HBV polymerase and inhibiting the virus replication.

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide is generally considered safe under controlled laboratory and clinical conditions. However, it is important to follow safety guidelines, including wearing appropriate personal protective equipment, and handling it in a well-ventilated area to avoid inhalation or skin contact.

2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide should be stored in a tightly sealed container at a temperature between 15-30°C (59-86°F) in a cool, dry place, away from direct sunlight and sources of heat. The storage container should be kept in a well-ventilated area and should not be exposed to moisture or humidity.