5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) | CAS No. 14358-90-8

5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

Basic Information

CAS Number

14358-90-8

Molecular Formula

C12H25NO5S2

Molecular Weight

327.47 g/mol

AD

Basic Physical Properties

C1CSSC1CCCCC(=O)O.C(C(CO)(CO)N)O

InChI

InChI=1S/C8H14O2S2.C4H11NO3/c9-8(10)4-2-1-3-7-5-6-11-12-7;5-4(1-6,2-7)3-8/h7H,1-6H2,(H,9,10);6-8H,1-3,5H2

InChIKey

CCTREOMTIFSZAU-UHFFFAOYSA-N

LogP

0.4459

Topological Polar Surface Area

124.01 Ų

Hydrogen Bond Donor/Acceptor

6 / 6

Complexity

204

Synonyms & References

English

  • Q27291650
  • 5-(1,2-Dithiolan-3-yl)pentanoic acid 2-amino-2-(hydroxymethyl)propane-1,3-diol salt
  • 14358-90-8
  • 1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, 1,2-DITHIOLANE-3-VALERATE (SALT)
  • V8276EBZ06
  • R-(+)-alpha-Lipoicacidtromethaminesalt
  • R-alpha-Lipoic acid tromethamine salt
  • NS00087353
  • 1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, 1,2-DITHIOLANE-3-PENTANOATE (SALT)
  • A808089
  • 1,2-Dithiolane-3-valeric acid, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
  • Thioctate trometamol
  • THIOCTATE TROMETAMOL [WHO-DD]
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol;5-(dithiolan-3-yl)pentanoic acid
  • DTXSID70931958
  • UNII-V8276EBZ06
  • FT-0774151
  • 5-(1,2-Dithiolan-3-yl)pentanoic acid--2-amino-2-(hydroxymethyl)propane-1,3-diol (1/1)
  • EINECS 238-329-9
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-(dithiolan-3-yl)pentanoic acid
  • 1,2-Dithiolane-3-valeric acid compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol,5-(dithiolan-3-yl)pentanoic acid
  • ALPHA LIPOIC ACID TRIMETHAMINE
  • 2-azanyl-2-(hydroxymethyl)propane-1,3-diol
  • 5-(1,2-dithiolan-3-yl)pentanoic acid
  • 5-(3-dithiolanyl)pentanoic acid
  • R-LIPOICACIDTROMETHAMINE
  • (R)-Lipoic Acid Tromethamine Salt
  • R(-)ALPHLALIPOICACIDTROMETHAMINESALT
  • R(A)ALPHA LIPOIC ACID TROMETHAMINE SALT
  • 1,2-dithiolane-3-valeric acid compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol

MDL Number

MFCD09032982

FAQ

What are the physical and chemical properties of 5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) (CAS: 14358-90-8)?

5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) is a crystalline compound with a molecular weight of approximately 330.31 g/mol. It has a moderate solubility in water and organic solvents. The compound exhibits good reactivity with thiol groups, making it useful in various applications. It is stable under normal laboratory conditions but should be stored in a cool, dry place away from direct sunlight.

How is 5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) (CAS: 14358-90-8) typically synthesized?

5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) is synthesized through a multi-step process involving the condensation of 2-amino-2-(hydroxymethyl)-1,3-propanediol with 5-(1,2-dithiolan-3-yl)pentanoic acid. This reaction typically requires an acidic catalyst and is carried out in a solvent such as methanol or ethanol. The yield is generally around 70-80%, depending on the purity of the starting materials and the efficiency of the reaction conditions.

What industries use 5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) (CAS: 14358-90-8)?

5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) is widely used in pharmaceuticals, polymers, and sensors. In pharmaceuticals, it plays a role in drug development and synthesis. In polymer science, it is used as a monomer for the production of biodegradable polymers. Additionally, it is employed in sensor technology for its ability to detect thiol compounds, making it valuable in environmental and industrial monitoring.

What precautions should be taken when handling 5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) (CAS: 14358-90-8)?

When handling 5-(1,2-Dithiolan-3-yl)pentanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its potential for inhalation. Spills should be cleaned up immediately with proper absorbent materials, and the area should be thoroughly washed. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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