N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide | CAS No. 1432660-47-3

N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide

Basic Information

CAS Number

1432660-47-3

Molecular Formula

C21H18F3N3O3S2

Molecular Weight

481.52 g/mol

AD

Basic Physical Properties

C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F

InChI

InChI=1S/C21H18F3N3O3S2/c22-21(23,24)14-2-1-3-16(10-14)25-20(28)26-19-11-17(32(29,30)27-15-4-5-15)6-7-18(19)13-8-9-31-12-13/h1-3,6-12,15,27H,4-5H2,(H2,25,26,28)

InChIKey

CCAWRGNYALGPQH-UHFFFAOYSA-N

LogP

5.518600000000002

Topological Polar Surface Area

87.3 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

771

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • AGI-6780
  • 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-ylphenyl]-3-[3-(trifluoromethyl)phenyl]urea
  • N-Cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide
  • AGI 6780
  • FD5013
  • QCR-283
  • N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide
  • AGI6780
  • AK162157
  • 1-[5-(Cyclopropylsulfamoyl)-2-Thiophen-3-Yl-Phenyl]-3-[3-(Trifluoromethyl)phenyl]urea
  • MLS006011046
  • C21H18F3N3O3S2
  • AOB2268
  • HMS3744K17
  • HMS3653I21
  • BDBM339679
  • BCP07383
  • US10202339, Compound 124
  • s7241
  • 2198AH
  • SB19578
  • NCGC0034
  • NSC781409
  • CHEMBL3392845
  • NCGC00347935-08
  • EX-A356
  • N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide
  • NCGC00347935-02
  • MFCD26097285
  • SCHEMBL15702521
  • 1K9

MDL Number

MFCD26097285

FAQ

What regulatory guidelines apply to N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3)?

N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) falls under various regulatory guidelines, including GHS classification for hazardous chemicals, REACH regulations for European manufacturers, and FDA/EPA requirements for safety and environmental protection. It is crucial to adhere to these guidelines to ensure the safe handling, transport, and disposal of the compound.

Are there alternatives to N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) in synthesis?

Several alternatives to N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) exist in synthesis, including analogs such as related thiophene-based compounds and isomers. Common alternative reagents include trifluoromethylated phenylureas and thiophene derivatives. These alternatives can offer similar functional groups or improved properties for specific applications.

What is the market or research trend for N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3)?

The market for N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) is driven by its use in pharmaceutical applications, particularly in the development of new drug candidates. Research trends focus on its ability to modulate specific biological pathways and its potential in treating various diseases. Additionally, there is an increasing interest in its synthesis and chemical properties, which are being explored for diverse applications.

How should waste containing N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) be handled?

Waste containing N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide (CAS: 1432660-47-3) should be collected and disposed of according to local and international regulations. Collection should be done in compatible containers to prevent contamination. For disposal, industrial incineration is a common method, while professional waste disposal services can also be utilized. It is essential to take appropriate environmental protection precautions to minimize the impact on the environment and public health.

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