2-Bromo-5-methoxypyrazine

Basic Information

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CAS Number

143250-10-6

Molecular Formula

C5H5BrN2O

Molecular Weight

189.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

208.5°C at 760 mmHg

Density

1.628

Flash Point

79.888 °C

SMILES

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COC1=CN=C(C=N1)Br

InChI

InChI=1S/C5H5BrN2O/c1-9-5-3-7-4(6)2-8-5/h2-3H,1H3

InChIKey

YMDHKDFBWIRZAZ-UHFFFAOYSA-N

LogP

1.2477

Topological Polar Surface Area

35.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Pyrazine, 2-bromo-5-methoxy-
SY021384
SCHEMBL421562
2-Bromo-5-methoxy-pyrazine
BCP23106
AKOS006284031
MFCD08235189
AM20070311
FS-2663
2-Bromo-5-methoxy-pyrazine;Pyrazine, 2-bromo-5-methoxy-
YMDHKDFBWIRZAZ-UHFFFAOYSA-N
FT-0648986
EN300-114919
143250-10-6
PB10528
Q-103283
2-bromo-5-methoxypyrazine
CS-W008616
DTXSID40599584
2-Bromo-5-methoxypyrazine
Pyrazine,2-bromo-5-methoxy-
2-Bromo-5-methoxy-1,4-diazine
2-bromo-5-methoxypyr
5-bromo-2-methoxypyrazine
FC0920
CB0084
STL556960
BBL103150
SBB054469
TRA0093701
RP03629

MDL Number

MFCD08235189

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6)?

2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous substance, specifically a respiratory sensitizer and skin irritant. It is also subject to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations in the European Union, requiring manufacturers and importers to register substances above a certain tonnage threshold. In the US, the Environmental Protection Agency (EPA) and Food and Drug Administration (FDA) may have specific requirements for its handling and use in agricultural and pharmaceutical applications.

Are there alternatives to 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) in synthesis?

While 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) is a specific compound with distinct properties, alternatives in synthesis can include other substituted pyrazines or brominated compounds. Common reagents like bromoacetyl bromide or substituted methoxypyrazines can serve as analogous starting materials. Researchers often explore these alternatives to achieve similar functional groups or properties without the specific structural requirements of 2-Bromo-5-methoxypyrazine.

What is the market or research trend for 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6)?

The market for 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) is growing due to its use in flavor and fragrance applications, as well as in the development of novel agrochemicals. Research trends focus on understanding its chemical properties, toxicity, and potential uses in food additives and as a flavor enhancer. Recent studies also explore its role in tobacco flavoring and its impact on food safety. The trend shows increasing demand for its use in the food industry, but caution is advised due to its regulatory status.

How should waste containing 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) be handled?

Waste containing 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) should be collected in appropriate containers that are resistant to chemical leakage. It should be stored in a well-ventilated area away from incompatible substances. Incineration or professional waste disposal services are recommended for safe disposal. Environmental precautions include ensuring that waste does not enter water systems or soil. Always follow local and national regulations for hazardous waste management, and consult with environmental protection authorities for specific disposal procedures.