What regulatory guidelines apply to 2-Bromo-5-methoxypyrazine (CAS: 143250-10-6)?

2-Bromo-5-methoxypyrazine (CAS: 143250-10-6) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous substance, specifically a respiratory sensitizer and skin irritant. It is also subject to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations in the European Union, requiring manufacturers and importers to register substances above a certain tonnage threshold. In the US, the Environmental Protection Agency (EPA) and Food and Drug Administration (FDA) may have specific requirements for its handling and use in agricultural and pharmaceutical applications.