N1-Me-pUTP, 100mM Solution

Basic Information

View in Editor

CAS Number

1428903-59-6

Molecular Formula

C10H17N2O15P3

Molecular Weight

498.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

P(=O)(O[H])(OP(=O)(O[H])OP(=O)(O[H])O[H])OC([H])([H])C1([H])C([H])(C([H])(C([H])(C2C(N([H])C(N(C([H])([H])[H])C=2[H])=O)=O)O1)O[H])O[H]

InChI

1S/C10H17N2O15P3/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)

InChIKey

OLRONOIBERDKRE-UHFFFAOYSA-N

LogP

-2.4213999999999984

Topological Polar Surface Area

264.36999999999995 Å²

Hydrogen Bond Donor/Acceptor

7 / 17

Complexity

884

Synonyms & References

English

n1-methylpseudouridine-5'-triphosphate
1-Methylpseudouridine-5'-triphosphate
N1-Methylpseudouridine-5′-triphosphate

FAQ

What are the physical and chemical properties of N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6)?

N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6) is a nucleoside triphosphate derivative. It has a crystalline form with a molecular weight of approximately 348.2 g/mol. It is soluble in water but insoluble in organic solvents. N1-Me-pUTP is reactive, particularly in chemical synthesis and biological applications due to its triphosphate group. It is used in various biological assays and as a substrate in enzymatic reactions.

How is N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6) typically synthesized?

N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6) is synthesized through the esterification of uridine monophosphate (UMP) with methylamine followed by the addition of a triphosphate group. Commonly, phosphoramidite chemistry is used for the triphosphorylation step. The synthesis typically involves multiple steps, with high yield and selectivity, and the use of appropriate catalysts and reagents.

What industries use N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6)?

N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6) is used in the pharmaceutical industry for the development of nucleotide-based drugs. It is also used in the biotechnology industry for molecular biology and genetic engineering applications. Additionally, it finds use in the semiconductor industry as a component in DNA biosensors and in polymer science for the synthesis of nucleotide-containing polymers.

What precautions should be taken when handling N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6)?

When handling N1-Me-pUTP, 100mM Solution (CAS: 1428903-59-6), ensure appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to prevent inhalation. Store the solution in a cool, dark place away from direct sunlight and heat sources. In case of spill, neutralize the solution with an appropriate neutralizing agent and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.