Cagrilintide | CAS No. 1415456-99-3
Cagrilintide
Basic Information
CAS Number
1415456-99-3
Molecular Formula
C194H312N54O59S2
Molecular Weight
4409 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Cagrilintide
- GLXC-26801
- 1415456-99-3
FAQ
What are the physical and chemical properties of Cagrilintide (CAS: 1415456-99-3)?
Cagrilintide (CAS: 1415456-99-3) is a small cyclic peptide with a molecular weight of approximately 1343.5 Da. It is water-soluble and can form crystalline forms under specific conditions. Cagrilintide has moderate reactivity towards harsh bases and is stable in neutral to slightly acidic environments. It does not readily undergo hydrolysis or oxidation under normal laboratory conditions.
How is Cagrilintide (CAS: 1415456-99-3) typically synthesized?
Cagrilintide (CAS: 1415456-99-3) is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The key steps involve coupling of amino acids and cleavage from the resin using trifluoroacetic acid (TFA). Commonly used coupling agents are DIC/HOBt, and the synthesis typically achieves a yield of about 70-80%. The selectivity and purity of the final product are ensured by HPLC purification.
What industries use Cagrilintide (CAS: 1415456-99-3)?
Cagrilintide (CAS: 1415456-99-3) is primarily used in the pharmaceutical industry for its anticoagulant properties. It is also utilized in the development of biosensors for thrombin detection due to its specific interaction with thrombin. Additionally, its structure makes it suitable for research in protein engineering and as a model compound for peptide-based materials.
What precautions should be taken when handling Cagrilintide (CAS: 1415456-99-3)?
When handling Cagrilintide (CAS: 1415456-99-3), it is important to wear personal protective equipment (PPE) such as gloves and a laboratory coat. Work should be conducted in a well-ventilated area or under a fume hood due to its potential reactivity. Spills should be cleaned up using appropriate absorbents and rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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