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Cagrilintide(CAS: 1415456-99-3)
CAS Number
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Basic Information
Molecular Formula
C194H312N54O59S2
Molecular Weight
4409 g/mol
Chemical Identifiers
SMILES
CCC(C)C(C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)N3CCCC3C(=O)N)NC(=O)C4CCCN4C(=O)CNC(=O)C(CC5=CC=CC=C5)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC6=CNC=N6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(C)NC(=O)C8CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N8)C(C)O)C)C(C)O)CC(=O)N)NC(=O)C(CCCCN)NC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O
InChIKey
LDERDVMBIYGIOI-DDPFBLHVSA-N
Database References
FAQ
Cagrilintide (CAS: 1415456-99-3) is a small cyclic peptide with a molecular weight of approximately 1343.5 Da. It is water-soluble and can form crystalline forms under specific conditions. Cagrilintide has moderate reactivity towards harsh bases and is stable in neutral to slightly acidic environments. It does not readily undergo hydrolysis or oxidation under normal laboratory conditions.
Cagrilintide (CAS: 1415456-99-3) is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The key steps involve coupling of amino acids and cleavage from the resin using trifluoroacetic acid (TFA). Commonly used coupling agents are DIC/HOBt, and the synthesis typically achieves a yield of about 70-80%. The selectivity and purity of the final product are ensured by HPLC purification.
Cagrilintide (CAS: 1415456-99-3) is primarily used in the pharmaceutical industry for its anticoagulant properties. It is also utilized in the development of biosensors for thrombin detection due to its specific interaction with thrombin. Additionally, its structure makes it suitable for research in protein engineering and as a model compound for peptide-based materials.
When handling Cagrilintide (CAS: 1415456-99-3), it is important to wear personal protective equipment (PPE) such as gloves and a laboratory coat. Work should be conducted in a well-ventilated area or under a fume hood due to its potential reactivity. Spills should be cleaned up using appropriate absorbents and rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
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