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(2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide | CAS No. 1401242-74-7

(2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide

Basic Information

Chemical_Structure_Of
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CAS Number

1401242-74-7

Molecular Formula

C23H25N3O4S2

Molecular Weight

471.6 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Ethers
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Insuluble (2.0E-4 g/L) (25 ºC),

SMILES

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CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C(=O)NC3=NC(=CS3)C4=CC=C(C=C4)OC

InChI

InChI=1S/C23H25N3O4S2/c1-16-6-12-19(13-7-16)32(28,29)26-14-4-3-5-21(26)22(27)25-23-24-20(15-31-23)17-8-10-18(30-2)11-9-17/h6-13,15,21H,3-5,14H2,1-2H3,(H,24,25,27)/t21-/m1/s1

InChIKey

OXQNLLVUVDAEHC-OAQYLSRUSA-N

LogP

4.309020000000003

Topological Polar Surface Area

88.60000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

728

Synonyms & References

English

  • (2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-[(4-methylphenyl) sulfonyl]-2-piperidinecarboxamide
  • ML 277
  • ML-277
  • ML277
  • VU0458298-3
  • 2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-, (2R)-
  • CHEMBL2070953
  • HY-12343
  • AS-16654
  • (2R)-N-[4-(4-METHOXYPHENYL)-1,3-THIAZOL-2-YL]-1-(4-METHYLBENZENESULFONYL)PIPERIDINE-2-CARBOXAMIDE
  • I0S
  • EX-A1076
  • Q27087069
  • AKOS024458340
  • J-690160
  • BDBM50390916
  • 1401242-74-7
  • MFCD28133374
  • (2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide
  • A906368
  • CS-3353
  • GTPL7666
  • NCGC00379200-06
  • (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide
  • SMR002532069
  • VU0458298-2
  • (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
  • (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide
  • MLS003875054
  • SCHEMBL20557492
  • BGC24274

MDL Number

MFCD01757771

FAQ

What are the physical and chemical properties of (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide (CAS: 1401242-74-7)?
(2R)-N-[4-(4-Methoxyphenyl)-1,3-Thiazol-2-yl]-1-(4-Methylphenyl)sulfonylpiperidine-2-Carboxamide (CAS: 1401242-74-7) is a crystalline compound with a molecular weight of approximately 507.66 g/mol. It is slightly soluble in water but has good solubility in organic solvents such as dichloromethane and acetonitrile. The compound is reactive towards nucleophiles and can undergo amide and sulfonyl group reactions. It is stable under normal laboratory conditions.

How is (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide (CAS: 1401242-74-7) typically synthesized?
(2R)-N-[4-(4-Methoxyphenyl)-1,3-Thiazol-2-yl]-1-(4-Methylphenyl)sulfonylpiperidine-2-Carboxamide (CAS: 1401242-74-7) can be synthesized via a multi-step process involving the condensation of a thiazole derivative with a piperidine ring, followed by sulfonation and coupling reactions. Common catalysts include various organic bases and Lewis acids, with yields typically ranging from 50% to 70%. The exact synthesis method may vary depending on the availability of raw materials and equipment.

What industries use (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide (CAS: 1401242-74-7)?
(2R)-N-[4-(4-Methoxyphenyl)-1,3-Thiazol-2-yl]-1-(4-Methylphenyl)sulfonylpiperidine-2-Carboxamide (CAS: 1401242-74-7) is primarily used in the pharmaceutical industry for its potential as a drug candidate. It may also find applications in the polymer and sensor industries due to its chemical structure and reactivity. Specific applications include the development of new antiviral and anticancer drugs, as well as use in organic electronic devices.

What precautions should be taken when handling (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide (CAS: 1401242-74-7)?
When handling (2R)-N-[4-(4-Methoxyphenyl)-1,3-Thiazol-2-yl]-1-(4-Methylphenyl)sulfonylpiperidine-2-Carboxamide (CAS: 1401242-74-7), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation and dermal exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly decontaminated. Always refer to the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions.

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(2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide — Shanghai Ruhui Chemical Technology Co., Ltd.

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