Compound Q&A

How is (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide (CAS: 1401242-74-7) typically synthesized?

Answer

(2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
(2R)-N-[4-(4-Methoxyphenyl)-1,3-Thiazol-2-yl]-1-(4-Methylphenyl)sulfonylpiperidine-2-Carboxamide (CAS: 1401242-74-7) can be synthesized via a multi-step process involving the condensation of a thiazole derivative with a piperidine ring, followed by sulfonation and coupling reactions. Common catalysts include various organic bases and Lewis acids, with yields typically ranging from 50% to 70%. The exact synthesis method may vary depending on the availability of raw materials and equipment.

About

English Name (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
Molecular Formula C23H25N3O4S2
Molecular Weight 471.6 g/mol
SMILES CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C(=O)NC3=NC(=CS3)C4=CC=C(C=C4)OC
InChIKey OXQNLLVUVDAEHC-OAQYLSRUSA-N
Last Updated: 2025-11-07 15:32

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