1-Cyclopropylpiperazine dihydrochloride

Basic Information

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CAS Number

139256-79-4

Molecular Formula

C7H16Cl2N2

Molecular Weight

199.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1CC1N2CCNCC2.Cl.Cl

InChI

InChI=1S/C7H14N2.2ClH/c1-2-7(1)9-5-3-8-4-6-9;;/h7-8H,1-6H2;2*1H

InChIKey

JDJNSFSTSJWJFA-UHFFFAOYSA-N

LogP

0.8976

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

93.1

Safety Information

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Hazard Class

Class 8 Class 8

Synonyms & References

English

SY064115
1-cyclopropylpiperazine di-hcl
A807510
1-cyclopropyl-piperazine, dihydrochloride
1-cyclopropylpiperazinedihydrochloride
1-Cyclopropyl-piperazine dihydrochloride
AMY5765
SCHEMBL64625
1-cyclopropyl-piperazine di-hcl
PS-8231
MFCD00040810
W-205529
SB20136
DTXSID90611447
1-cyclopropyl-piperazine 2 hcl
AC-31185
1-cyclopropylpiperazine dihydrochloride
AKOS015911689
JDJNSFSTSJWJFA-UHFFFAOYSA-N
139256-79-4
1-Cyclopropyl-piperazine bis-hydrochloride
Piperazine, 1-cyclopropyl-, dihydrochloride
1-cyclopropyl-piperazine x 2 hcl
1-cyclopropylpiperazine;dihydrochloride
1-CYCLOPROPYLPIPERAZINE 2HCL
1-Cyclopropylpiperazine--hydrogen chloride (1/2)
CS-0054714
Piperazine, 1-cyclopropyl-, hydrochloride (1:2)
FT-0643303
Piperazine,1-cyclopropyl-,hydrochloride(1:2)
1-cyclopropylpiperazine-bis-hydrochloric acid

MDL Number

MFCD00040810

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-Cyclopropylpiperazine dihydrochloride (CAS: 139256-79-4)?

1-Cyclopropylpiperazine dihydrochloride is a crystalline white powder with a molecular weight of approximately 214.76 g/mol. It is soluble in water, ethanol, and other polar solvents. The compound is relatively stable under normal conditions, but it reacts with bases to form the free base. It is also sensitive to light and should be stored in a light-protective container.

How is 1-Cyclopropylpiperazine dihydrochloride (CAS: 139256-79-4) typically synthesized?

1-Cyclopropylpiperazine dihydrochloride is commonly synthesized by the reaction of cyclopropylamine with piperazine followed by hydrochloric acid treatment. The reaction is carried out in an inert atmosphere, and the product is isolated by crystallization. The yield is typically around 70%, and the reaction is selective under the chosen conditions.

What industries use 1-Cyclopropylpiperazine dihydrochloride (CAS: 139256-79-4)?

1-Cyclopropylpiperazine dihydrochloride is primarily used in the pharmaceutical industry for the development of central nervous system drugs. It is also used in the preparation of certain organic compounds and as a precursor in the synthesis of other complex molecules. Minor applications are found in the polymer industry for special applications requiring specific chemical properties.

What precautions should be taken when handling 1-Cyclopropylpiperazine dihydrochloride (CAS: 139256-79-4)?

When handling 1-Cyclopropylpiperazine dihydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from direct sunlight. Spills should be carefully managed using appropriate absorbents, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.