1-Cyclopropylpiperazine dihydrochloride(CAS: 139256-79-4)

1-Cyclopropylpiperazine dihydrochloride is a crystalline white powder with a molecular weight of approximately 214.76 g/mol. It is soluble in water, ethanol, and other polar solvents. The compound is relatively stable under normal conditions, but it reacts with bases to form the free base. It is also sensitive to light and should be stored in a light-protective container.

1-Cyclopropylpiperazine dihydrochloride is commonly synthesized by the reaction of cyclopropylamine with piperazine followed by hydrochloric acid treatment. The reaction is carried out in an inert atmosphere, and the product is isolated by crystallization. The yield is typically around 70%, and the reaction is selective under the chosen conditions.

1-Cyclopropylpiperazine dihydrochloride is primarily used in the pharmaceutical industry for the development of central nervous system drugs. It is also used in the preparation of certain organic compounds and as a precursor in the synthesis of other complex molecules. Minor applications are found in the polymer industry for special applications requiring specific chemical properties.

When handling 1-Cyclopropylpiperazine dihydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from direct sunlight. Spills should be carefully managed using appropriate absorbents, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.