(2R)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid

Basic Information

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CAS Number

138775-02-7

Molecular Formula

C18H24N2O6

Molecular Weight

364.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

518.9°C at 760 mmHg

SMILES

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CC(C)(C)OC(=O)N1CCN(C[C@@H]1C(=O)O)C(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C18H24N2O6/c1-18(2,3)26-17(24)20-10-9-19(11-14(20)15(21)22)16(23)25-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,22)/t14-/m1/s1

InChIKey

SREPAMKILVVDSP-CQSZACIVSA-N

LogP

2.3291000000000004

Topological Polar Surface Area

96.38000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 8

Complexity

524

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-N-1-BOC-N-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID
(R)-4-Cbz-1-Boc-Piperazine-2-carboxylic acid
(R)-4-((Benzyloxy)carbonyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
(2R)-4-[(Benzyloxy)carbonyl]-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
(R)-4-((Benzyloxy)carbonyl)-1-(tert-butoxycarbonyl)-piperazine-2-carboxylic acid
(R)-4-(benzyloxycarbonyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
(2R)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenylmethoxycarbonylpiperazine-2-carboxylic acid
(r)-1-boc-4-cbz-2-piperazine carboxylic acid
(R)-1-N-BOC-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID
(r)-1-boc-4-cbz-piperazine-2-carboxylic acid
(2r)-piperazine-1,2,4-tricarboxylic acid 4-benzyl ester 1-tert-butyl ester
(2r)-4-[(benzyloxy)car
(2R)-4-benzyloxycarbonyl-1-tert-butoxycarbonyl-piperazine-2-carboxylic acid

MDL Number

MFCD02179112

Customs Code

2933599090

FAQ

What regulatory guidelines apply to (2R)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid (CAS: 138775-02-7)?

The compound must comply with the REACH regulations in the European Union, ensuring that manufacturers and importers register substances above a certain tonnage threshold. Additionally, it should adhere to the Globally Harmonized System (GHS) for classification and labeling of chemicals, including appropriate hazard communication. In the United States, it must meet FDA and EPA requirements, focusing on safe handling, storage, and disposal to protect human health and the environment.

Are there alternatives to (2R)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid (CAS: 138775-02-7) in synthesis?

There are alternative reagents, such as (2S)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid or other piperazine derivatives, which can be used as alternatives in synthesis. These alternatives may offer similar functionality but with different reactivity and selectivity, providing flexibility in the design of synthetic routes.

What is the market or research trend for (2R)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid (CAS: 138775-02-7)?

There is a growing interest in the compound for its potential in drug discovery and development, particularly in the field of kinase inhibitors. Market trends indicate increasing research and development efforts, driven by its structural complexity and biological activity. Price trends suggest stability, but fluctuations may occur based on supply and demand dynamics.

How should waste containing (2R)-4-[(Benzyloxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid (CAS: 138775-02-7) be handled?

Waste containing this compound should be collected and disposed of according to local regulations. It is advisable to incinerate the waste at a licensed facility to ensure complete destruction. Environmental protection precautions include proper containment during collection and transportation to prevent spillage. Additionally, the waste should be minimized through efficient use and recycling, where applicable, to reduce overall environmental impact.