4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid | CAS No. 138279-32-0

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid

Basic Information

CAS Number

138279-32-0

Molecular Formula

C15H13Cl2NO4

Molecular Weight

342.18 g/mol

AD

Basic Physical Properties

CC1=C(C(C(=C(N1)C)C(=O)O)c2cccc(c2Cl)Cl)C(=O)O

InChI

InChI=1S/C15H13Cl2NO4/c1-6-10(14(19)20)12(11(15(21)22)7(2)18-6)8-4-3-5-9(16)13(8)17/h3-5,12,18H,1-2H3,(H,19,20)(H,21,22)

InChIKey

GCUMHOAQJSSYSV-UHFFFAOYSA-N

LogP

3.397400000000001

Topological Polar Surface Area

86.63000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Synonyms & References

English

  • 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid
  • Clevidipine Butyrate Impurity I
  • Felodipine Diacid
  • AK-93576
  • ANW-53336
  • BD230960
  • CTK8B6360
  • KB-237272
  • SureCN2563899
  • UNII-08U7I74079
  • 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5- dicarboxylic acid

MDL Number

MFCD22421639

FAQ

What are the physical and chemical properties of 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid (CAS: 138279-32-0)?

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid is a white or off-white crystalline solid with a molecular weight of approximately 340.03 g/mol. It has a high melting point and low solubility in water. This compound is moderately reactive, typically showing ester-like behavior. It can undergo thermal degradation and reacts with bases, acids, and oxidizing agents.

How is 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid (CAS: 138279-32-0) typically synthesized?

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid is synthesized through the condensation of 2,3-dichloroaniline and adipic acid. The synthesis typically involves multi-step reactions and requires careful control of temperature and pH. Catalysts such as p-toluenesulfonic acid (p-TSA) are used to increase the reaction rate and yield. The final product is isolated by crystallization from an appropriate solvent.

What industries use 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid (CAS: 138279-32-0)?

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid finds applications in the pharmaceutical industry for intermediate production, and in the polymer industry for the synthesis of certain types of resins. It is also used in the development of sensors and in semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid (CAS: 138279-32-0)?

When handling 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid, proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. This compound is a potential skin and eye irritant, so it is advisable to use forceps for handling and avoid contact with skin and eyes. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled in a fume hood and cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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