4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid(CAS: 138279-32-0)

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid is a white or off-white crystalline solid with a molecular weight of approximately 340.03 g/mol. It has a high melting point and low solubility in water. This compound is moderately reactive, typically showing ester-like behavior. It can undergo thermal degradation and reacts with bases, acids, and oxidizing agents.

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid is synthesized through the condensation of 2,3-dichloroaniline and adipic acid. The synthesis typically involves multi-step reactions and requires careful control of temperature and pH. Catalysts such as p-toluenesulfonic acid (p-TSA) are used to increase the reaction rate and yield. The final product is isolated by crystallization from an appropriate solvent.

4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid finds applications in the pharmaceutical industry for intermediate production, and in the polymer industry for the synthesis of certain types of resins. It is also used in the development of sensors and in semiconductor manufacturing due to its unique chemical properties.

When handling 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylic acid, proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. This compound is a potential skin and eye irritant, so it is advisable to use forceps for handling and avoid contact with skin and eyes. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled in a fume hood and cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.