2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite | CAS No. 137348-88-0
2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite
Basic Information
CAS Number
137348-88-0
Molecular Formula
C16H37N2OP
Molecular Weight
304.46 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
67-74 °C
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- J-007007
- TERT-BUTYL TETRAISOPROPYLPHOSPHORO-DIAMIDITE
- AKOS025294435
- SCHEMBL2479770
- N-[[di(propan-2-yl)amino]-[(2-methylpropan-2-yl)oxy]phosphanyl]-N-propan-2-ylpropan-2-amine
- DTXSID40399086
- FT-0710386
- tert-Butyl tetraisopropylphosphorodiamidite, 95%
- 137348-88-0
- tert-Butyl tetraisopropylphosphorodiamidite
- Phosphorodiamidousacid, N,N,N',N'-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester
- TERT-BUTYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORODIAMIDITE
- (tert-Butoxy)bis(diisopropylamino)phosphine
- [tert-butyloxy]bis(N,N-diisopropylamino)phosphane
- Phosphorodiamidousacid,tetrakis(1-methylethyl)-,1,1-dimethylethyl ester (9CI)
- tert-butyl N,N,N',N'-tetraisopropylphosphorodiamidite
- tert-butyl tetraisopropylphosphordiamidite
MDL Number
MFCD00674022
FAQ
What are the physical and chemical properties of 2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0)?
2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0) is a colorless viscous liquid with a high molecular weight. It has a low solubility in water but is soluble in organic solvents. It is moderately reactive and can undergo hydrolysis and other chemical transformations. This compound is stable under normal storage conditions but should be handled with care due to its reactivity.
How is 2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0) typically synthesized?
2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0) is synthesized through multistep organic reactions involving the coupling of isopropyl phosphites with appropriate amine derivatives. This process typically requires mild to moderate conditions and may involve the use of common organic solvents and catalysts. The yield and selectivity depend on the specific reaction conditions.
What industries use 2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0)?
2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0) is primarily used in the pharmaceutical, polymer, and semiconductor industries. It serves as a precursor in the synthesis of various pharmaceutical compounds and can be used in the manufacture of certain polymers and semiconductor materials due to its unique chemical properties.
What precautions should be taken when handling 2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0)?
When handling 2-Methyl-2-propanyl N,N,N',N'-tetraisopropylphosphorodiamidoite (CAS: 137348-88-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbents and disposed of according to laboratory safety protocols. Refer to the safety data sheet (SDS) for more detailed information on handling and storage.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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