(3S)-3-Fluoropyrrolidine hydrochloride (1:1)

Basic Information

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CAS Number

136725-53-6

Molecular Formula

C4H9ClFN

Molecular Weight

125.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

183-187 °C

Boiling Point

91°Cat760mmHg

Flash Point

8.8°C

SMILES

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C1CNCC1F.Cl

InChI

InChI=1S/C4H8FN.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3H2;1H/t4-;/m0./s1

InChIKey

LENYOXXELREKGZ-WCCKRBBISA-N

LogP

0.7396000000000003

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

46.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Prone to absorbing moisture

Synonyms & References

English

(S)-3-FLUOROPYRROLIDINE HCL
(S)-(-)-3-fluoropyrrolidine hydrochloride
AM20080270
CS-W004695
(5)-3-fluoropyrrolidine hydrochloride
136725-53-6
(5)-(+)-3-fluoropyrrolidine hydrochloride
PS-9190
(S)-3-floropyrrolidine hydrogen chloride
(3S)-3-Fluoropyrrolidine--hydrogen chloride (1/1)
(S)(+)3-fluoropyrrolidine hydrochloride
C4H9ClFN
(S)-(+)-3-FLUOROPYRROLIDINE, HCL
Pyrrolidine, 3-fluoro-, hydrochloride (1:1), (3S)-
AKOS005255415
(S)-(+)-3-Fluoropyrrolidine hydrochloride, 97%
HY-W004695
LENYOXXELREKGZ-WCCKRBBISA-N
(S)-(+)-3-fluoropyrrolidine hydrochloric acid
(3S)-3-fluoropyrrolidin hydrochloride
MFCD04038718
(s)-3-fluoropyrrolidine hydrochloride
(S)-3-fluoropyrrolidin hydrochloride
DTXSID50584527
(S)-3-Fluoropyrrolidine (hydrochloride)
J-006898
SCHEMBL717319
EN300-243764
S-3-fluoropyrrolidine hydrochloride
(3S)-3-fluoropyrrolidine hydrochloride
(S)-(+)-3-Fluoropyrrolidine hydrochloride

MDL Number

MFCD04038718

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6)?

(3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) is a white crystalline powder. The molecular weight is approximately 116.56 g/mol. It is sparingly soluble in water and moderately soluble in ethanol. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions.

How is (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) typically synthesized?

(3S)-3-Fluoropyrrolidine hydrochloride can be synthesized by a variety of methods, including the reaction of 3-fluoropyrrolidin-3-ol with hydrochloric acid. This process typically involves the use of a stoichiometric amount of hydrochloric acid, leading to a yield of around 85-90%. The reaction is performed under mild conditions to ensure high selectivity.

What industries use (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6)?

(3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in polymer chemistry for the development of new materials, and in the production of sensors and semiconductors for electronic devices.

What precautions should be taken when handling (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6)?

When handling (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, use appropriate safety measures and consult the Material Safety Data Sheet (MSDS) for guidance.