(3S)-3-Fluoropyrrolidine hydrochloride (1:1)(CAS: 136725-53-6)

(3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) is a white crystalline powder. The molecular weight is approximately 116.56 g/mol. It is sparingly soluble in water and moderately soluble in ethanol. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions.

(3S)-3-Fluoropyrrolidine hydrochloride can be synthesized by a variety of methods, including the reaction of 3-fluoropyrrolidin-3-ol with hydrochloric acid. This process typically involves the use of a stoichiometric amount of hydrochloric acid, leading to a yield of around 85-90%. The reaction is performed under mild conditions to ensure high selectivity.

(3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in polymer chemistry for the development of new materials, and in the production of sensors and semiconductors for electronic devices.

When handling (3S)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, use appropriate safety measures and consult the Material Safety Data Sheet (MSDS) for guidance.