Ranatachykinin A

Basic Information

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CAS Number

135690-47-0

Molecular Formula

C60H92N16O15S

Molecular Weight

1309.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)NC(=O)C3CCCN3C(=O)C(CO)NC(=O)C4CCCN4C(=O)C(CCCCN)N

InChI

InChI=1S/C60H92N16O15S/c1-34(2)28-41(53(85)69-39(50(63)82)22-27-92-3)68-48(79)32-67-51(83)42(30-36-18-20-37(78)21-19-36)71-54(86)43(29-35-12-5-4-6-13-35)72-52(84)40(15-9-24-66-60(64)65)70-55(87)44(31-49(80)81)73-56(88)47-17-11-26-76(47)59(91)45(33-77)74-57(89)46-16-10-25-75(46)58(90)38(62)14-7-8-23-61/h4-6,12-13,18-21,34,38-47,77-78H,7-11,14-17,22-33,61-62H2,1-3H3,(H2,63,82)(H,67,83)(H,68,79)(H,69,85)(H,70,87)(H,71,86)(H,72,84)(H,73,88)(H,74,89)(H,80,81)(H4,64,65,66)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1

InChIKey

CBWGJMUZXSIZFG-CIRMSXBNSA-N

LogP

-4.069400000000009

Topological Polar Surface Area

510.70999999999987 Å²

Hydrogen Bond Donor/Acceptor

21 / 31

Complexity

2520

Synonyms & References

English

Ranatachykinin A
BDBM50087851
Eledoisin, 1-L-lysine-4-L-proline-6-L-arginine-8-L-tyrosine-
135690-47-0
RTK A
RTK-A
DTXSID90159495
LysProSerProAspArgPheTyrGlyLeuMet
Ranatachykinin a(9ci)
CHEMBL384518
Lys-pro-ser-pro-asp-arg-phe-tyr-gly-leu-met-NH2
Ranatachykinin A (9CI)
H-LYS-PRO-SER-PRO-ASP-ARG-PHE-TYR-GLY-LEU-MET-NH2
RANATACHYKININ A
LYS-PRO-SER-PRO-ASP-ARG-PHE-TYR-GLY-LEU-MET-NH2

MDL Number

MFCD00237247

FAQ

What are the physical and chemical properties of Ranatachykinin A (CAS: 135690-47-0)?

Ranatachykinin A (CAS: 135690-47-0) is a cyclic decapeptide with a molecular weight of approximately 1241.45 Da. It is highly soluble in water and has a crystalline form with a melting point around 220°C. It is stable in acidic and basic conditions but can degrade upon exposure to light and heat.

How is Ranatachykinin A (CAS: 135690-47-0) typically synthesized?

Ranatachykinin A (CAS: 135690-47-0) is synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly, the peptide is assembled in a stepwise manner, with each amino acid being added sequentially. The final product is then cleaved from the solid support using trifluoroacetic acid (TFA). This method typically yields a 70-80% purity.

What industries use Ranatachykinin A (CAS: 135690-47-0)?

Ranatachykinin A (CAS: 135690-47-0) is primarily used in pharmaceutical research for its potential as a receptor antagonist. It also has applications in the development of peptide-based drugs and as a tool compound in peptide chemistry research. Its use is limited to research and not for commercial or industrial applications.

What precautions should be taken when handling Ranatachykinin A (CAS: 135690-47-0)?

When handling Ranatachykinin A (CAS: 135690-47-0), laboratory personnel should wear appropriate personal protective equipment (PPE) including gloves and safety glasses. The compound should be stored in a cool, dark place to prevent degradation. Fume hoods should be used during synthesis and handling to minimize inhalation. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for more detailed information on handling and storage.