3-(4-bromophenyl)-1,2-oxazol-5-ol | CAS No. 1354930-93-0

3-(4-bromophenyl)-1,2-oxazol-5-ol

Basic Information

CAS Number

1354930-93-0

Molecular Formula

C9H6BrNO2

Molecular Weight

240.06 g/mol

AD

Basic Physical Properties

Brc1ccc(cc1)c1noc(c1)O

InChI

InChI=1S/C9H6BrNO2/c10-7-3-1-6(2-4-7)8-5-9(12)13-11-8/h1-5,12H

InChIKey

YABZERPSCWKKCO-UHFFFAOYSA-N

LogP

2.8097000000000008

Topological Polar Surface Area

46.260000000000005 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

  • 3-(4-bromophenyl)-1,2-oxazol-5-ol
  • 3-(4-Bromophenyl)-5-hydroxyisoxazole

MDL Number

MFCD21334962

FAQ

What are the physical and chemical properties of 3-(4-bromophenyl)-1,2-oxazol-5-ol (CAS: 1354930-93-0)?

3-(4-Bromophenyl)-1,2-oxazol-5-ol is a crystalline solid with a molecular weight of approximately 278.05 g/mol. It has a low water solubility, making it unsuitable for aqueous solutions. This compound is relatively stable but can react with strong bases. It exhibits good solubility in organic solvents such as dichloromethane and ethanol.

How is 3-(4-bromophenyl)-1,2-oxazol-5-ol (CAS: 1354930-93-0) typically synthesized?

3-(4-Bromophenyl)-1,2-oxazol-5-ol is synthesized through a multistep process involving bromination, followed by an oxazolization reaction. Commonly, bromobenzene is brominated to form 4-bromophenol, which is then reacted with a nitrile in the presence of a base to form the oxazol-5-ol derivative.

What industries use 3-(4-bromophenyl)-1,2-oxazol-5-ol (CAS: 1354930-93-0)?

3-(4-Bromophenyl)-1,2-oxazol-5-ol is used in the pharmaceutical industry for the synthesis of various organic compounds. It also finds applications in the sensor industry due to its reactivity and stability. Additionally, it is utilized in the semiconductor industry as a precursor in the fabrication of electronic materials.

What precautions should be taken when handling 3-(4-bromophenyl)-1,2-oxazol-5-ol (CAS: 1354930-93-0)?

Proper personal protective equipment (PPE) is essential when handling 3-(4-bromophenyl)-1,2-oxazol-5-ol, including gloves, goggles, and a lab coat. Ensure the work is conducted in a well-ventilated fume hood to minimize exposure to bromine compounds. In case of spill, follow the safety data sheet (SDS) guidelines for disposal, and avoid contact with eyes and skin.

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