3-(4-bromophenyl)-1,2-oxazol-5-ol(CAS: 1354930-93-0)

3-(4-Bromophenyl)-1,2-oxazol-5-ol is a crystalline solid with a molecular weight of approximately 278.05 g/mol. It has a low water solubility, making it unsuitable for aqueous solutions. This compound is relatively stable but can react with strong bases. It exhibits good solubility in organic solvents such as dichloromethane and ethanol.

3-(4-Bromophenyl)-1,2-oxazol-5-ol is synthesized through a multistep process involving bromination, followed by an oxazolization reaction. Commonly, bromobenzene is brominated to form 4-bromophenol, which is then reacted with a nitrile in the presence of a base to form the oxazol-5-ol derivative.

3-(4-Bromophenyl)-1,2-oxazol-5-ol is used in the pharmaceutical industry for the synthesis of various organic compounds. It also finds applications in the sensor industry due to its reactivity and stability. Additionally, it is utilized in the semiconductor industry as a precursor in the fabrication of electronic materials.

Proper personal protective equipment (PPE) is essential when handling 3-(4-bromophenyl)-1,2-oxazol-5-ol, including gloves, goggles, and a lab coat. Ensure the work is conducted in a well-ventilated fume hood to minimize exposure to bromine compounds. In case of spill, follow the safety data sheet (SDS) guidelines for disposal, and avoid contact with eyes and skin.