4-Fluoro-3-methylbenzaldehyde

Basic Information

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CAS Number

135427-08-6

Molecular Formula

C8H7FO

Molecular Weight

138.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

208 °C

Water Solubility

Slightly soluble in water.

Refractive Index

n20/D 1.522(lit.)

SMILES

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CC1=C(C=CC(=C1)C=O)F

InChI

InChI=1S/C8H7FO/c1-6-4-7(5-10)2-3-8(6)9/h2-5H,1H3

InChIKey

NRFKZFFVTGGEQF-UHFFFAOYSA-N

LogP

1.94662

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

124

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

H227

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H227 Combustible liquid
Flammable liquids

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

J-006695
3-METHYL-4-FLUOROBENZALDEHYDE
3-methyl-4-fluoro benzaldehyde
AM61761
EN300-61152
AC-3847
4-Fluoro-3-methylbenzaldehyde, 97%
4-Fluoro-3-Methyl benzaldehyde
AKOS005254609
4-FLUORO-3- METHYLBENZALDEHYDE
Benzaldehyde, 4-fluoro-3-methyl-
SCHEMBL336067
J-515354
F0791
4-fluoro-3-methyl-benzaldehyde
F0001-0459
SY017835
CS-W007668
MFCD01631431
Z732814060
NRFKZFFVTGGEQF-UHFFFAOYSA-N
4-Fluoro-3-methylbenzaldehyde
DTXSID90370547
InChI=1/C8H7FO/c1-6-4-7(5-10)2-3-8(6)9/h2-5H,1H
PS-9082
4-FLUORO-M-TOLUALDEHYDE
FT-0618541
135427-08-6
4-Fluoro-m-tolualdehyde
3-Methyl-4-fluorobenzaldehyde
3-methyl-4-flurobenzaldehyde

MDL Number

MFCD01631431

Customs Code

2913000090

FAQ

What are the physical and chemical properties of 4-Fluoro-3-methylbenzaldehyde (CAS: 135427-08-6)?

4-Fluoro-3-methylbenzaldehyde is a colorless to light yellow liquid with a molecular weight of approximately 160.13 g/mol. It has a melting point of -38°C and a boiling point of 190°C. The compound is slightly soluble in water but miscible with common organic solvents. It is moderately reactive, particularly with nucleophiles and reducing agents.

How is 4-Fluoro-3-methylbenzaldehyde (CAS: 135427-08-6) typically synthesized?

4-Fluoro-3-methylbenzaldehyde is commonly synthesized via the method of acylation of 3-methyl-4-fluorophenol with acetyl chloride in the presence of a catalytic amount of aluminum chloride. This process provides good yield and selectivity, with careful control of reaction conditions ensuring the desired product is formed.

What industries use 4-Fluoro-3-methylbenzaldehyde (CAS: 135427-08-6)?

4-Fluoro-3-methylbenzaldehyde finds applications in the pharmaceutical industry, where it is used as a precursor for the synthesis of various drugs. It is also utilized in the production of certain polymers and as a component in the development of sensors and semiconductors.

What precautions should be taken when handling 4-Fluoro-3-methylbenzaldehyde (CAS: 135427-08-6)?

When handling 4-Fluoro-3-methylbenzaldehyde, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat sources and oxidizing agents. In case of a spill, use an appropriate absorbent material and consult the Material Safety Data Sheet (MSDS) for further guidance.