2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate

Basic Information

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CAS Number

1352999-04-2

Molecular Formula

C12H24N2O2

Molecular Weight

228.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC(C)(C)OC(=O)NCC1(N)CCCCC1

InChI

InChI=1S/C12H24N2O2/c1-11(2,3)16-10(15)14-9-12(13)7-5-4-6-8-12/h4-9,13H2,1-3H3,(H,14,15)

InChIKey

CMEHRZGJNHKUAN-UHFFFAOYSA-N

LogP

2.1727

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

240

Synonyms & References

English

TERT-BUTYL N-[(1-AMINOCYCLOHEXYL)METHYL]CARBAMATE
TERT-BUTYL ((1-AMINOCYCLOHEXYL)METHYL)CARBAMATE
tert-Butyl [(1-aminocyclohexyl)methyl]carbamate
PB32019
tert-butyl N-[(1-aminocyclohexyl)methyl]carbamate

MDL Number

MFCD21091404

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate (CAS: 1352999-04-2)?

2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate is a colorless or pale yellow liquid with a molecular weight of approximately 269.38 g/mol. It has a moderate solubility in water and is highly soluble in organic solvents. This compound is relatively stable but can undergo hydrolysis in aqueous solutions. It has a pKa of around 8.5, indicating basic properties.

How is 2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate (CAS: 1352999-04-2) typically synthesized?

2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate can be synthesized via a multi-step process involving the coupling of 1-aminocyclohexanecarbonyl chloride with 2-methyl-2-propanol. The reaction typically uses triethylamine as a base and is performed in anhydrous dichloromethane. The yield is around 75-80%, with good selectivity for the desired product.

What industries use 2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate (CAS: 1352999-04-2)?

2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate is primarily used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in the polymer industry, where it serves as a stabilizer and modifier. Additionally, it is used in the manufacturing of sensors and semiconductors for its unique chemical reactivity.

What precautions should be taken when handling 2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate (CAS: 1352999-04-2)?

When handling 2-Methyl-2-propanyl [(1-aminocyclohexyl)methyl]carbamate, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be cleaned up immediately using a suitable absorbent material. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.