4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione | CAS No. 1352827-50-9

4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

Basic Information

CAS Number

1352827-50-9

Molecular Formula

C14H13N3O4

Molecular Weight

287.28 g/mol

AD

Basic Physical Properties

CN1C(=O)CCC(N2C(=O)c3cccc(N)c3C2=O)C1=O

InChI

InChI=1S/C14H13N3O4/c1-16-10(18)6-5-9(13(16)20)17-12(19)7-3-2-4-8(15)11(7)14(17)21/h2-4,9H,5-6,15H2,1H3

InChIKey

YSWQOCGODHPKED-UHFFFAOYSA-N

LogP

0.012199999999999656

Topological Polar Surface Area

100.78 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

532

Synonyms & References

English

  • 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • 4-amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
  • E3 Ligase ligand methylated negative control
  • 4-amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione

MDL Number

MFCD31703382

FAQ

What are the physical and chemical properties of 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione (CAS: 1352827-50-9)?

4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione is a crystalline solid with a molecular weight of approximately 314.34 g/mol. It is slightly soluble in water and organic solvents. The compound is stable under normal conditions but reacts with acids to form salts. It is also susceptible to hydrolysis under acidic conditions.

How is 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione (CAS: 1352827-50-9) typically synthesized?

4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione is synthesized via a multi-step process involving condensation reactions and ring formation. Commonly, it is prepared from 4-formylisoindoline-1,3(2H)-dione and 1-methyl-2,6-piperidinedione. The synthesis requires precise control of temperature and pH to achieve high yield and selectivity.

What industries use 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione (CAS: 1352827-50-9)?

4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione is primarily used in the pharmaceutical industry for the production of certain drugs. It is also utilized in the polymer industry for developing functional materials, and in the sensor industry for its ability to interact with specific analytes.

What precautions should be taken when handling 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione (CAS: 1352827-50-9)?

When handling 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area, such as a fume hood, due to its potential to release toxic vapors. In case of a spill, immediately clean it up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions.

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