![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
{(3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile | CAS No. 133099-09-9
{(3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile
Basic Information
CAS Number
133099-09-9
Molecular Formula
C25H24N2O2S
Molecular Weight
416.5 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- SCHEMBL3229344
- A806555
- (S)-2,2-diphenyl-2-(1-tosyl-3-pyrrolidinyl)acetonitrile
- 3-(S)-(1-cyano-1,1-diphenylmethyl)-1-tosylpyrrolidine
- (S)-2,2-diphenyl-2-(1-tosylpyrrolidin-3-yl)acetonitrile
- 2-[(3S)-1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]-2,2-diphenylacetonitrile
- AC-8864
- F15228
- CS-M0900
- CS-13241
- (S)-Diphenyl-[1-(toluene-4-sulfonyl)-pyrrolidin-3-yl]-acetonitrile
- (3S)-1-Tosyl-alpha,alpha-diphenyl-3-pyrrolidineacetonitrile
- AKOS015895850
- C25H24N2O2S
- Q-101009
- 133099-09-9
- (S)-3-(1-CYANO-1,1-DIPHENYLMETHYL)-1-TOSYLPYRROLIDINE
- MFCD11616859
- [(3S)-1-(4-Methylbenzene-1-sulfonyl)pyrrolidin-3-yl](diphenyl)acetonitrile
- 3-(S)-(+)-(1-cyano-1,1-diphenylmethyl)-1-tosylpyrrolidine
- 3-Pyrrolidineacetonitrile, 1-[(4-methylphenyl)sulfonyl]-alpha,alpha-diphenyl-, (3S)-
- XPQZNOFTICUMIN-HSZRJFAPSA-N
- DTXSID00628647
- 3-(S)-(1-Cyano-1,1-diphenylmethyl)-1-tosylpyrrolidine
- (s)-3-(1-cyano-1,1-diphenylmethyl)-1-tosyloxypyrrolidine (Darifenacin)
- (3S)- 1-[(4-methylphenyl)sulfonyl]-diphenyl-3-Pyrrolidineacetonitrile
- (s)-3-(1-cyano-1,1-diphenylmethyl)-1-tosyloxypyrrolidine
- (S)-2,2-Diphenyl-2-(1-tosyl-3-pyrrolidinyl)acetonitrile
- (3S)-1-Tosyl-α,α-diphenyl-
- (S)-3-(1-Cyano-1,1-diphenylmethyl)-1-tosylpyrrolidine
- Darifenacin Intermediate III
MDL Number
MFCD11616859
FAQ
What are the physical and chemical properties of (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile (CAS: 133099-09-9)?
The physical properties of (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile include a crystalline form with a molecular weight of approximately 565.65 g/mol. It has low water solubility but good solubility in organic solvents such as dimethylformamide and acetonitrile. Chemically, it is moderately reactive, particularly towards nucleophiles and can undergo acylation reactions with good yield.
How is (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile (CAS: 133099-09-9) typically synthesized?
This compound is typically synthesized via the condensation of (4-methylphenyl)sulfonyl chloride with (3S)-3-pyrrolidinyl-diphenylacetonitrile. The reaction is catalyzed by a strong base like sodium hydride, and the process involves high selectivity, with a yield of up to 85%.
What industries use (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile (CAS: 133099-09-9)?
This compound is used in various industries, including pharmaceuticals for developing specific drug candidates, and in materials science for polymer synthesis and sensor technology. It is also explored in semiconductor manufacturing for its unique chemical properties.
What precautions should be taken when handling (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile (CAS: 133099-09-9)?
Proper personal protective equipment (PPE) is essential when handling this compound, including gloves, goggles, and lab coats. Work should be done in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and all safety data sheets (SDS) should be consulted for specific handling and disposal instructions.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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