Compound Q&A
How is (3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile (CAS: 133099-09-9) typically synthesized?
Answer
![{(3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile](https://static.chemtradehub.com/structs/133/133099-09-9-2c07.webp "{(3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile")
This compound is typically synthesized via the condensation of (4-methylphenyl)sulfonyl chloride with (3S)-3-pyrrolidinyl-diphenylacetonitrile. The reaction is catalyzed by a strong base like sodium hydride, and the process involves high selectivity, with a yield of up to 85%.
About
CAS No
133099-09-9
English Name
{(3S)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinyl}(diphenyl)acetonitrile
Molecular Formula
C25H24N2O2S
Molecular Weight
416.5 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)N2CCC(C2)C(C#N)(C3=CC=CC=C3)C4=CC=CC=C4
InChIKey
XPQZNOFTICUMIN-HSZRJFAPSA-N
Last Updated: 2025-10-13 11:18
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