Sodium 4-amino-2-hydroxybenzoate

Basic Information

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CAS Number

133-10-8

Molecular Formula

C7H6NNaO3

Molecular Weight

175.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

150-151 deg C, with effervescence

Boiling Point

380.8 °C at 760 mmHg

Density

1.491

Flash Point

184.1 °C

SMILES

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C1=CC(=C(C=C1N)O)C(=O)[O-].[Na+]

InChI

InChI=1S/C7H7NO3.Na/c8-4-1-2-5(7(10)11)6(9)3-4;/h1-3,9H,8H2,(H,10,11);/q;+1/p-1

InChIKey

FVVDKUPCWXUVNP-UHFFFAOYSA-M

LogP

-0.08090

Complexity

165

Synonyms & References

English

HMS1920C11
AMINOSALICYLATE SODIUM [WHO-DD]
MLS000069500
SW219149-1
HMS2091I11
Pasalon-rakeet
FVVDKUPCWXUVNP-UHFFFAOYSA-M
Tox21_111696
CCG-212479
AKOS006229752
Pasade
p-Aminosalicylic acid sodium salt
4-AMINOSALICYLIC ACID SODIUM SALT
Monosodium 4-amino-2-hydroxybenzoate
Monosodium T4-amino-2-hydroxybenzoate
Nippas
Sodium PAS
sodium 4-azanyl-2-oxidanyl-benzoate
4-Amino-2-hydroxybenzoic acid sodium salt
SPECTRUM1500116
C08055
Salicylic acid, 4-amino-, sodium salt
CHEBI:2661
NCGC00094584-01
sodium 4-amino-2-hydroxy-benzoate
A0423
Salvis
MFCD00064392
Passodico
CAS-133-10-8
sodium 4-amino-2-hydroxybenzoate

MDL Number

MFCD00064392

Customs Code

2918219000

FAQ

What are the physical and chemical properties of Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8)?

Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8) is a white crystalline solid with a molecular weight of approximately 220.14 g/mol. It has a pKa of about 4.8 and is slightly soluble in water. The compound is reactive and can undergo hydrolysis and substitution reactions. It has a melting point of 233-235°C and a boiling point of around 340°C under reduced pressure.

How is Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8) typically synthesized?

Sodium 4-amino-2-hydroxybenzoate is typically synthesized by reacting 4-amino-2-hydroxybenzoic acid with sodium hydroxide. The reaction is carried out in an aqueous medium, and the product is isolated by crystallization. Commonly used methods include direct neutralization and ion exchange techniques, yielding a product with high selectivity and good yield.

What industries use Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8)?

Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8) is used in the pharmaceutical industry as a precursor for the synthesis of various medicinals. It is also utilized in the polymer industry for the modification of certain polymers and in the production of sensors and semiconductors due to its functional groups.

What precautions should be taken when handling Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8)?

When handling Sodium 4-amino-2-hydroxybenzoate (CAS: 133-10-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or within a fume hood to avoid inhalation. Spills should be cleaned up using appropriate materials and procedures as outlined in the Safety Data Sheet (SDS). Ensure proper storage and disposal according to regulatory requirements.