(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine | CAS No. 132335-46-7

(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine

Basic Information

CAS Number

132335-46-7

Molecular Formula

C19H21NOS

Molecular Weight

311.45 g/mol

AD

Basic Physical Properties

Boiling Point

459.744°C at 760 mmHg

CN(C)CCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32

InChI

InChI=1S/C19H21NOS/c1-20(2)13-12-18(19-11-6-14-22-19)21-17-10-5-8-15-7-3-4-9-16(15)17/h3-11,14,18H,12-13H2,1-2H3/t18-/m0/s1

InChIKey

JFTURWWGPMTABQ-SFHVURJKSA-N

LogP

4.973100000000004

Topological Polar Surface Area

12.47 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

335

Synonyms & References

English

  • 2-Thiophenepropanamine, N,N-dimethyl-gamma-(1-naphthalenyloxy)-
  • (s)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
  • 2241983-09-3
  • N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl) propylamine
  • 3-[(1-Naphthyl-4-D)oxy]-N,N-dimethyl-3-(2-thienyl)-1-propanamine
  • (+/-)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
  • N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
  • N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
  • AKOS015962082
  • S-(+)-N,N-Dimethyl-3-(1-Naphthlenyloxy)-3-(2-Thienyl)-Propanamine
  • SB49719
  • (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl) propan-1-amine
  • SY246338
  • Duloxetine IMpurity 09
  • Duloxetinehydrochloride
  • N,N-Dimethyl-3-[(naphthalen-1-yl)oxy]-3-(thiophen-2-yl)propan-1-amine
  • AC-15713
  • 2-Thiophenepropanamine, N,N-dimethyl-gamma-(1-naphthalenyloxy)-, (gammaR)-
  • JFTURWWGPMTABQ-UHFFFAOYSA-N
  • (RS)-N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine
  • Duloxetine IMpurity 08
  • 132335-46-7
  • N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
  • racemic N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
  • DTXSID10468814
  • FT-0652452
  • MFCD31699967
  • 878757-08-5
  • SCHEMBL12342733
  • BCP19501
  • J-006163

MDL Number

MFCD08458281

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (CAS: 132335-46-7)?

(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine is a solid with a crystalline form. Its molecular weight is approximately 322.32 g/mol. It has limited solubility in water but is more soluble in organic solvents like methanol and ethanol. This compound is known for its stability in air and does not react readily with common reagents. It is not flammable and has a low vapor pressure, making it safe for handling under normal laboratory conditions.

How is (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (CAS: 132335-46-7) typically synthesized?

(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine can be synthesized through a multi-step process involving the reaction of naphthalene, thiophene, and dimethylamine. The synthesis typically requires the use of a catalyst, such as a palladium complex, to ensure high selectivity and yield. The final product can be isolated by recrystallization from an appropriate solvent, ensuring purity for further applications.

What industries use (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (CAS: 132335-46-7)?

(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine finds applications in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It may also be used in the polymer industry for the development of new materials with specific properties. Additionally, this compound can be utilized in the field of sensors and semiconductors due to its chemical structure and reactivity.

What precautions should be taken when handling (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (CAS: 132335-46-7)?

When handling (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up immediately using appropriate techniques and materials. For detailed safety information, refer to the safety data sheet (SDS) for this compound.

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