3-Chloro-4-nitropyridine

Basic Information

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CAS Number

13194-60-0

Molecular Formula

C5H3ClN2O2

Molecular Weight

158.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

25-26 ºC

Boiling Point

256 ºC

Flash Point

108 ºC

SMILES

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C1=CN=CC(=C1[N+](=O)[O-])Cl

InChI

InChI=1S/C5H3ClN2O2/c6-4-3-7-2-1-5(4)8(9)10/h1-3H

InChIKey

CWLVEHGKYCYAIO-UHFFFAOYSA-N

LogP

2.16640

Complexity

136

Synonyms & References

English

MFCD00490146
3-chloro-4-nitro-pyridine
A806336
AMY22908
13194-60-0
Pyridine,3-chloro-4-nitro-
AB06349
SCHEMBL827098
CS-W005126
FT-0650312
AC-27968
SY010069
AKOS015850487
Pyridine, 3-chloro-4-nitro-
DS-11345
DTXSID90376564
3-chloro-4-nitropyridine
3-Chloro-4-nitropyridine
3-Chlor-4-nitro-pyridin
3-chloranyl-4-nitro-pyridine
Pyridine,3-chloro-4-nitro
100G,,2.5W
RP22212
RP22208
FCH1120330
VP13680
OR345250
ST2410627
AX8085880
AB0035471
X9816

MDL Number

MFCD00490146

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 3-Chloro-4-nitropyridine (CAS: 13194-60-0)?

3-Chloro-4-nitropyridine (CAS: 13194-60-0) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous substance. It is classified under GHS categories: Skin corrosion/irritation Category 2, Serious eye damage/eye irritation Category 2, and Specific target organ toxicity (single exposure) Category 3 (respiratory tract irritation). In Europe, it is covered by REACH regulations, requiring manufacturers and importers to register it if the quantity used or imported exceeds one tonne per year. It is also listed under the U.S. EPA's Toxic Substances Control Act (TSCA) and the FDA's regulations for the safety of chemical substances.

Are there alternatives to 3-Chloro-4-nitropyridine (CAS: 13194-60-0) in synthesis?

While 3-Chloro-4-nitropyridine is a versatile intermediate in some synthetic routes, there are alternatives depending on the specific application. For example, 4-chloro-3-nitropyridine and 2-chloro-5-nitropyridine can be used as substitutes. In the synthesis of pyridine derivatives, 2-chloro-6-nitropyridine and 3-nitro-2-pyridone can also serve as effective alternatives. However, the choice of alternative often depends on the desired properties of the final product and the reactivity of the substituents.

What is the market or research trend for 3-Chloro-4-nitropyridine (CAS: 13194-60-0)?

The market for 3-Chloro-4-nitropyridine (CAS: 13194-60-0) reflects its use in various industries, including pharmaceuticals, agrochemicals, and fine chemicals. Recent research trends indicate an increasing focus on the development of novel pyridine derivatives for medicinal applications, particularly in the treatment of inflammatory and neurodegenerative diseases. Market analysis suggests steady demand, with price stability due to consistent production and moderate consumption. Emerging research is exploring its use in cancer therapy and as a precursor in organic synthesis.

How should waste containing 3-Chloro-4-nitropyridine (CAS: 13194-60-0) be handled?

Handling waste containing 3-Chloro-4-nitropyridine (CAS: 13194-60-0) requires careful consideration due to its hazardous nature. Waste should be collected in appropriate containers and stored separately to prevent contamination. For laboratory-scale waste, it is recommended to neutralize the waste with a base before disposal. For larger quantities, professional waste disposal services should be utilized. Proper incineration is a common method, but it must be conducted in compliance with local regulations. Environmental protection measures include ensuring no hazardous materials leach into the soil or groundwater, and all disposal activities should follow GHS guidelines to ensure worker safety.