3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione

Basic Information

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CAS Number

131807-57-3

Molecular Formula

C22H18N2O4

Molecular Weight

374.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

140.3～141.8℃

Boiling Point

491.3±55.0°C at 760 mmHg

Density

1.3270

Refractive Index

1.659

SMILES

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CC1(C(=O)N(C(=O)O1)Nc2ccccc2)c3ccc(cc3)Oc4ccccc4

InChI

InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3

InChIKey

PCCSBWNGDMYFCW-UHFFFAOYSA-N

LogP

4.700000000000004

Topological Polar Surface Area

67.87 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

563

Safety Information

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GHS Hazard Pictograms

H225

H302

H312

H319

H332

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

Toxicity

LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Joshi, Sternberg)

Synonyms & References

English

5-Methyl-5-(4-phenoxyphenyl)-3-(phenylamino)oxazolidine-2,4-dione
5-Methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-2,4-oxazolidinedione
Famoxadone solution
Famoxadone
3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
FAMOXADON
(RS)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
3-Anilino-5-methyl-5-(4-phenoxyphenyl)oxazolidine-2,4-dione
DPX-JE 874
Famoxate
rac-(5R)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
JE 874
CCharisma
IN-JE 874
FaMoxadone solutio
famoxadone (bsi, pa iso)
DPX-JE874
Famoxadon
FAMOXADONE
famoxadone solution

MDL Number

MFCD03427409

FAQ

What is 3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione (CAS: 131807-57-3)?

3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione (CAS: 131807-57-3) is a chemical compound with a unique structure that includes an oxazolidine ring, an anilino group, and a phenoxyphenyl group. It is a white or off-white solid with a molecular weight of approximately 417.31 u.

What are the main uses of 3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione (CAS: 131807-57-3)?

3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione is primarily used as a pharmaceutical intermediate for the synthesis of various drugs. It is also used in the production of certain dyes and in organic synthesis due to its unique functional groups.

Is 3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione (CAS: 131807-57-3) safe?

3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione is generally considered safe for its intended use, but proper handling is necessary. It is not toxic by ingestion, but contact with skin or eyes should be avoided. Storage in a cool, dry place away from direct sunlight is recommended. Always follow appropriate safety guidelines and wear protective gear when handling this compound.

How should 3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione (CAS: 131807-57-3) be stored?

3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture and air. The compound is stable when stored under these conditions, and it is advisable to check its expiration date and use it within the recommended timeframe for optimal performance.