3-Chloro-2-hydroxypropyl methacrylate

Basic Information

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CAS Number

13159-52-9

Molecular Formula

C7H11ClO3

Molecular Weight

178.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

No data available

Boiling Point

108°C/5mmHg

Refractive Index

n20/D 1.475(lit.)

SMILES

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CC(=C)C(=O)OCC(CCl)O

InChI

InChI=1S/C7H11ClO3/c1-5(2)7(10)11-4-6(9)3-8/h6,9H,1,3-4H2,2H3

InChIKey

DDKMFQGAZVMXQV-UHFFFAOYSA-N

LogP

0.7054

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

156

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

AKOS015916537
1-Chloro-3-methacryloxy-2-propanol
2-Propenoic acid, 2-methyl-, 3-chloro-2-hydroxypropyl ester
MFCD00040686
SCHEMBL129034
3-Chloro-2-hydroxypropyl methacrylate, stabilized with HQ
EINECS 236-097-3
C2105
3-Chloro-2-hydroxypropyl Methacrylate (stabilized with HQ)
J-006025
DTXSID30884512
13159-52-9
NS00052006
?3-CHLORO-2-HYDROXYPROPYL METHACRYLATE
(3-chloro-2-hydroxypropyl) 2-methylprop-2-enoate
3-Chloro-2-hydroxypropyl Methacrylate, (stabilized with HQ)
VS-08631
DDKMFQGAZVMXQV-UHFFFAOYSA-N
FT-0741555
3-Chloro-2-hydroxypropyl methacrylate
CHPMA
F71320
3-chloro-2-hydroxypropyl 2-methylprop-2-enoate
Methacrylic Acid 3-Chloro-2-hydroxypropyl Ester
2-Propenoic acid,2-methyl-, 3-chloro-2-hydroxypropyl ester
3-Chloro-2-hydroxypropyl Methacrylate
Methacrylic Acid 3-Chloro-2-hydroxypropyl Ester (stabilized with HQ)
Methacrylicacid, 3-chloro-2-hydroxypropyl ester (7CI,8CI)
1,2-Propanediol, 3-chloro-,1-methacrylate (8CI)
2-Hydroxy-3-chloropropyl methacrylate
3-Chloro-2-hydroxyprop-1-ylmethacrylate

MDL Number

MFCD00040686

Customs Code

2916140000

FAQ

What are the physical and chemical properties of 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9)?

3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9) is a colorless to yellowish liquid with a molecular weight of approximately 196.57 g/mol. It has a pKa of around 2.3 and is slightly soluble in water. The compound is known for its reactivity, especially under acidic conditions, and it can participate in polymerization reactions efficiently.

How is 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9) typically synthesized?

3-Chloro-2-hydroxypropyl methacrylate is typically synthesized via the methacrylation of 3-chloro-2-hydroxypropyl chloride with methacryloyl chloride. Common catalysts include strong bases such as sodium hydride. The process usually involves a one-step reaction with good yield and selectivity, making it a practical method for industrial production.

What industries use 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9)?

3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9) is widely used in the pharmaceutical, polymer, and sensor industries due to its reactive properties. It serves as a building block in the synthesis of various polymers and is also utilized in the development of medical devices and sensors.

What precautions should be taken when handling 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9)?

When handling 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate materials, and the material safety data sheet (MSDS) should be consulted for proper disposal procedures.