3-Chloro-2-hydroxypropyl methacrylate(CAS: 13159-52-9)

3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9) is a colorless to yellowish liquid with a molecular weight of approximately 196.57 g/mol. It has a pKa of around 2.3 and is slightly soluble in water. The compound is known for its reactivity, especially under acidic conditions, and it can participate in polymerization reactions efficiently.

3-Chloro-2-hydroxypropyl methacrylate is typically synthesized via the methacrylation of 3-chloro-2-hydroxypropyl chloride with methacryloyl chloride. Common catalysts include strong bases such as sodium hydride. The process usually involves a one-step reaction with good yield and selectivity, making it a practical method for industrial production.

3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9) is widely used in the pharmaceutical, polymer, and sensor industries due to its reactive properties. It serves as a building block in the synthesis of various polymers and is also utilized in the development of medical devices and sensors.

When handling 3-Chloro-2-hydroxypropyl methacrylate (CAS: 13159-52-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate materials, and the material safety data sheet (MSDS) should be consulted for proper disposal procedures.