(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone | CAS No. 130403-91-7
(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone
Basic Information
CAS Number
130403-91-7
Molecular Formula
C10H21NO2Si
Molecular Weight
215.37 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- (S)-3-(tert-butyldimethylsilyloxy)-2-pyrrolidinone
- (S)-3-((Tert-Butyldimethylsilyl)Oxy)Pyrrolidin-2-One
MDL Number
MFCD26394938
FAQ
What are the physical and chemical properties of (3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7)?
(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7) is a colorless to white crystalline solid with a molecular weight of approximately 286.4 g/mol. It has low water solubility and moderate solubility in organic solvents like methanol and acetonitrile. Chemically, it is highly reactive towards nucleophiles and can undergo various transformations under specific conditions, such as hydrolysis or silyl group displacement.
How is (3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7) typically synthesized?
(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone is usually synthesized via a silylation reaction of the corresponding pyrrolidone with dimethyl(2-methyl-2-propanyl)silane in the presence of a base, such as triethylamine. The reaction is typically carried out in an aprotic solvent like tetrahydrofuran (THF) at low temperature to achieve high yield and selectivity.
What industries use (3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7)?
(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drug compounds. It is also utilized in the polymer industry for modifying the chemical properties of polymers, and in the semiconductor industry for its use in organic light-emitting diodes (OLEDs) due to its electron-donating properties.
What precautions should be taken when handling (3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7)?
Precautions when handling (3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone (CAS: 130403-91-7) include wearing appropriate personal protective equipment (PPE), such as lab coats, gloves, and safety goggles. The substance should be handled in a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety and handling instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![(3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-pyrrolidinone — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}