5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine | CAS No. 130339-07-0
5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine
Basic Information
CAS Number
130339-07-0
Molecular Formula
C15H16ClF2N3O
Molecular Weight
327.76 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
46～50℃
Boiling Point
431.796°C at 760 mmHg
Density
1.294
Flash Point
214.943°C
Refractive Index
1.565
Synonyms & References
English
- 4-PYRIMIDINAMINE, 5-CHLORO-N-(1-(4-(DIFLUOROMETHOXY)PHENYL)PROPYL)-6-METHYL-, (+/-)-
- HGZ4LD5DT9
- UNII-HGZ4LD5DT9
- 4-PYRIMIDINAMINE, 5-CHLORO-N-(1-(4-(DIFLUOROMETHOXY)PHENYL)PROPYL)-6-METHYL-
- CHEBI:82861
- 5-CHLORO-N-(1-(4-(DIFLUOROMETHOXY)PHENYL)PROPYL)-6-METHYL-4-PYRIMIDINAMINE
- DTXSID1057955
- UBF-002
- Diflumetorim
- NEKULYKCZPJMMJ-UHFFFAOYSA-N
- SCHEMBL23037
- NS00133788
- FUMIJUNAN
- 5-chloro-N-[1-[4-(difluoromethoxy)phenyl]propyl]-6-methylpyrimidin-4-amine
- 130339-07-0
- Q19278300
- Diflumetorim [ISO]
- PYRICUT
- 5-chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-amine
- 4-Pyrimidinamine,5-chloro-N-[1-[4-(difluoromethoxy)phenyl]propyl]-6-methyl-
- (RS)-5-chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-ylamine
- 5-chloro-N-[1-[4-(difluoromethoxy)phenyl]propyl]-6-methyl-4-pyrimidinamine
- rac-5-chloro-N-{(1R)-1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-amine
- ubf-002
- Diflumetorim [iso]
- DIFLUMETORIM STANDARD
- diflumetorim (bsi, pa iso)
MDL Number
MFCD03427396
FAQ
What are the physical and chemical properties of 5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine (CAS: 130339-07-0)?
The compound 5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine has a crystalline form and a molecular weight of approximately 411.2 g/mol. It has low water solubility but is soluble in organic solvents like DMSO. Chemically, it exhibits moderate reactivity, particularly towards nucleophilic substitution reactions.
How is 5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine (CAS: 130339-07-0) typically synthesized?
This compound is synthesized via a multi-step process typically involving coupling reactions and protecting group strategies. Commonly, a trifunctional amine is reacted with a difluoromethoxy-substituted phenyl acetylene, followed by coupling with a methylated pyrimidine derivative. The synthesis often employs palladium catalysts and requires high selectivity and yield for efficient production.
What industries use 5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine (CAS: 130339-07-0)?
5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine is primarily used in the pharmaceutical industry due to its biological activity. It may also find applications in the semiconductor industry for specific electronic properties and in the polymer industry for specialized polymers.
What precautions should be taken when handling 5-Chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methyl-4-pyrimidinamine (CAS: 130339-07-0)?
Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling this compound. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, immediately clean up with appropriate absorbent materials and ensure proper disposal. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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