Quinine Hydrochloride

Basic Information

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CAS Number

130-89-2

Molecular Formula

C20H25ClN2O2

Molecular Weight

360.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

150-160°C

Refractive Index

1.5400 (estimate)

SMILES

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Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

InChI=1S/C20H24N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H/t13-,14-,19-,20+;/m0./s1

InChIKey

LBSFSRMTJJPTCW-DSXUQNDKSA-N

LogP

3.5950000000000024

Topological Polar Surface Area

45.59 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

Quinine hydrochloride
(8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride
QUININE HCL
CINCHONAN-9-OL,6'-METHOXY-, HYDROCHLORIDE (1:1), (8ALPHA,9R)-
PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
QUININE HYDROCHLORIDE DIHYDRATE
QUININE MONO HCL
QUININE MONOHYDROCHLORIDE
QUININE MONOHYDROCHLORIDE DIHYDRATE
chinimetten
quininemuriate
quininechloride
Quinine HCL & Sulfate
Hydrochloric acid quinine
Quinine·hydrochloric acid
QUININE HYDROCHLORIDE 2 H2O
quinine, monohydrochloride

MDL Number

MFCD00078498

Customs Code

2939200000

FAQ

What is Quinine Hydrochloride (CAS: 130-89-2)?

Quinine hydrochloride is an alkaloid with the chemical formula C20H24N2O2·HCl. It is a white crystalline substance with a bitter taste and a distinctive smell. It is highly soluble in water and less soluble in ethanol. It is best known for its antimalarial properties and is also used in the treatment of post-dural puncture headache and intermittent claudication.

What are the main uses of Quinine Hydrochloride (CAS: 130-89-2)?

Quinine hydrochloride is primarily used as an antimalarial medication. It is also used to treat post-dural puncture headache and intermittent claudication. In pharmaceuticals, it is often included in combination drugs. Additionally, it has been used experimentally in research for various conditions related to its anti-inflammatory, antipyretic, and anti-arrhythmic properties.

Is Quinine Hydrochloride (CAS: 130-89-2) safe?

Quinine hydrochloride is generally considered safe when used as directed. However, it can cause side effects such as dizziness, nausea, and hypoglycemia. It should be used with caution, especially in individuals with kidney or liver disease. Pregnant and breastfeeding women should avoid it. Always consult a healthcare provider before using quinine hydrochloride.

How should Quinine Hydrochloride (CAS: 130-89-2) be stored?

Quinine hydrochloride should be stored in a dry place away from light and moisture. It should be kept in a tightly closed container to prevent moisture absorption. The storage temperature should be below 30°C (86°F) to maintain its efficacy. Avoid direct sunlight and high humidity, as these conditions can degrade the compound. Storing it in a cool, dry place is recommended for optimal storage conditions.