Dapoxetine Hydrochloride

Basic Information

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CAS Number

129938-20-1

Molecular Formula

C21H24ClNO

Molecular Weight

341.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

179.0 to 183.0 deg-C

Solubility

DMSO: ≥20mg/mL

Specific Rotation

D +135.78° (c = 2.18 in methanol)

SMILES

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CN(C)C(CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3.Cl

InChI

InChI=1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1

InChIKey

IHWDIQRWYNMKFM-BDQAORGHSA-N

LogP

5.3334000000000055

Topological Polar Surface Area

12.47 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

337

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H413 May cause long lasting harmful effects to aquatic life
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

(1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine;hydrochloride
D03649
129938-20-1 (HCl)
KS-5240
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-aminehydrochloride
F15016
LY-210448 hydrochloride
DAPOXETINE HYDROCHLORIDE [MI]
(S)-N,N-Dimethyl-?-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
D4761
LY 210448 hydrochloride
Benzenemethanamine, N,N-dimethyl-alpha-(2-(1-naphthalenyloxy)ethyl)-, hydrochloride, (S)-
Benzenemethanamine, N,N-dimethyl-a-[2-(1-naphthalenyloxy)ethyl]-,hydrochloride, (S)-
EX-A4046
s1869
Priligy
(S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propylamine Hydrochloride
D-dapoxetine HCL
LY210448 HCl
(S)-N,N-Dimethyl-<span class='symbol'>alpha</span>-[2-(1-naphthaleny loxy)ethyl]benzenemethanamine hydrochloride
Dapoxetine hydrochloride (Priligy)
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
Dapoxetine hydrochloride (USAN)
Dapoxetine .hcl
LY-210448 hydrochloride;(S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride
Dapoxetine hydrochloride
AKOS015889488
HY-B0304A
(S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropylamine Hydrochloride
(+)-(S)-N,N-Dimethyl-alpha-(2-(1-naphthyloxy)ethyl)benzylamine hydrochloride
129938-20-1

MDL Number

MFCD08272809

Customs Code

2922199090

FAQ

What is Dapoxetine Hydrochloride (CAS: 129938-20-1)?

Dapoxetine Hydrochloride (CAS: 129938-20-1) is a selective serotonin reuptake inhibitor (SSRI) primarily used in pharmaceuticals. Its chemical formula is C19H22N2O2·HCl, and it is known for its potency in treating premature ejaculation. The compound is a white crystalline powder with good solubility in water, making it suitable for oral administration in drug formulations.

What are the main uses of Dapoxetine Hydrochloride (CAS: 129938-20-1)?

Dapoxetine Hydrochloride (CAS: 129938-20-1) is mainly used as a medication for the treatment of premature ejaculation. It works by selectively inhibiting serotonin reuptake, enhancing ejaculation control. Additionally, it is utilized in research for studying erectile dysfunction and as an intermediate in pharmaceutical synthesis. Its applications are limited to medical and scientific contexts due to specific regulatory approvals.

Is Dapoxetine Hydrochloride (CAS: 129938-20-1) safe?

Dapoxetine Hydrochloride (CAS: 129938-20-1) is considered safe when used as prescribed, with a well-established safety profile in clinical settings. However, improper handling may pose risks, so it is recommended to use protective gloves and ensure proper ventilation. Safety standards include adherence to FDA guidelines and GMP regulations for pharmaceutical use, emphasizing controlled exposure and quality assurance.

How should Dapoxetine Hydrochloride (CAS: 129938-20-1) be stored?

Dapoxetine Hydrochloride (CAS: 129938-20-1) should be stored in a cool, dry place (ideally 25°C), away from moisture and direct light. Keep in a sealed, airtight container to maintain stability and prevent degradation. Storage precautions include avoiding exposure to high humidity and ensuring it is kept in a secure location to prevent unauthorized access or misuse.