Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide | CAS No. 127-58-2

Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide

Basic Information

CAS Number

127-58-2

Molecular Formula

C11H11N4NaO2S

Molecular Weight

286.29 g/mol

AD

Basic Physical Properties

Melting Point

Not available

Boiling Point

Not available

Density

Not available

Water Solubility

Soluble in DMSO or water

Flash Point

Not available

Vapor Pressure

Not available

CC1=NC(=NC=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]

InChI

InChI=1S/C11H11N4O2S.Na/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10;/h2-7H,12H2,1H3;/q-1;+1

InChIKey

BSFJGCCAXDCMOX-UHFFFAOYSA-N

LogP

2.68880

Complexity

365

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation

Synonyms & References

English

  • Sulfamerazine sodium salt
  • SULFAMERAZINE MONOSODIUM SALT [MI]
  • sodium;(4-aminophenyl)sulonyl-(4-methylpyrimidin-2-yl)azanide
  • SULFAMERAZINE SODIUM [INJECTION]
  • CHEBI:201395
  • AT25528
  • sodium;4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
  • SULFAMERAZINE SODIUM [MART.]
  • Sulfamerazine monosodium salt
  • NSC 226823
  • Sulfanilamide, N(sup 1)-(4-methyl-2-pyrimidinyl)-, monosodium salt
  • Sulfamerazine (sodium salt)
  • sodium (4-aminophenylsulfonyl)(4-methylpyrimidin-2-yl)amide
  • HY-B0512A
  • Sulfamerazina sodica
  • Sodium derivate of N1-(4-methyl-2-pyrimidinyl)sulfanilamide
  • Sulfamerazine sodium [Injection] [INN:NF]
  • Q27281612
  • NS00041928
  • methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
  • J-005506
  • SULFAMERAZINESODIUM
  • Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)
  • SR-01000883950-1
  • Sulfamerazinum natricum [INN-Latin]
  • SR-01000883950
  • Sulfamerazin natrium
  • DTXSID1051644
  • JOV4UJY07O
  • 127-58-2
  • Sulfamerazine sodium [INN]

MDL Number

MFCD00068332

FAQ

What are the physical and chemical properties of Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide (CAS: 127-58-2)?

Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide is a crystalline compound with a molecular weight of approximately 455.35 g/mol. It has a density of about 1.47 g/cm³ and a melting point of around 245°C. This compound is sparingly soluble in water but more soluble in organic solvents. It is known for its reactivity, particularly in nucleophilic substitution reactions.

How is Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide (CAS: 127-58-2) typically synthesized?

Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide is typically synthesized through a multi-step process involving the reaction of 4-aminophenyl sulfonyl chloride with 4-methyl-2-pyrimidinyl azide. The reaction proceeds under basic conditions, and the yield is moderate. This synthesis requires careful control of temperature and pH to ensure high selectivity.

What industries use Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide (CAS: 127-58-2)?

Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide finds applications in pharmaceuticals, where it is used as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the development of functional materials and in the field of sensors for its reactivity and stability.

What precautions should be taken when handling Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide (CAS: 127-58-2)?

When handling Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Handling should be performed in a well-ventilated area or a fume hood to prevent inhalation of dust. In case of spills, they should be cleaned up using appropriate absorbents and the area should be properly decontaminated. Always consult the Safety Data Sheet (SDS) for detailed safety guidelines.

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