7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine | CAS No. 1269667-51-7

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine

Basic Information

CAS Number

1269667-51-7

Molecular Formula

C6H3BrClN3

Molecular Weight

232.47 g/mol

AD

Basic Physical Properties

C1=C2C(=NC=NN2C(=C1)Br)Cl

InChI

InChI=1S/C6H3BrClN3/c7-5-2-1-4-6(8)9-3-10-11(4)5/h1-3H

InChIKey

WHHDFKYGOMDNGN-UHFFFAOYSA-N

LogP

2.1452

Topological Polar Surface Area

30.19 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

157

Synonyms & References

English

  • 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine
  • 7-bromo-4-chloro-pyrrolo[2,1-f][1,2,4]triazine
  • FT-0685184
  • PB30370
  • PYRROLO[2,1-F][1,2,4]TRIAZINE, 7-BROMO-4-CHLORO-
  • RP08655
  • 7-bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine
  • SCHEMBL865545
  • AS-38694
  • 1269667-51-7
  • DB-207959
  • SY042383
  • W-205261
  • CS-0050075
  • WHHDFKYGOMDNGN-UHFFFAOYSA-N
  • MFCD19443913
  • Z1269215669
  • J-519136
  • DTXSID60735088
  • EN300-182890
  • AKOS015949481

MDL Number

MFCD19443913

FAQ

What are the physical and chemical properties of 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine (CAS: 1269667-51-7)?

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is a crystalline solid with a molecular weight of approximately 263.01 g/mol. Its solubility in water is minimal. This compound is moderately reactive and can undergo substitution reactions. It is insoluble in common organic solvents but soluble in polar aprotic solvents like dimethylformamide (DMF).

How is 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine (CAS: 1269667-51-7) typically synthesized?

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is typically synthesized via a multistep procedure involving the reaction of 4-chloropyrrolo[2,1-f][1,2,4]triazine with bromine in the presence of a base such as sodium hydroxide. The reaction requires careful control of temperature and pH to achieve high yield and selectivity.

What industries use 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine (CAS: 1269667-51-7)?

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is used in the pharmaceutical industry for the synthesis of certain drug candidates due to its structural complexity. It may also find applications in polymer chemistry for the modification of organic materials and in the development of sensors and semiconductors.

What precautions should be taken when handling 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine (CAS: 1269667-51-7)?

Proper handling of 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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